24 citations
,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)” This study found that in women with polycystic ovary syndrome, a pulse-based diet was more effective than the TLC diet at improving insulin sensitivity and cardiometabolic risk factors, although both diets improved PCOS-specific health outcomes.
35 citations
,
June 1997 in “Annals of the New York Academy of Sciences” Early diagnosis and multidisciplinary care are crucial for managing PCOS in adolescents.
July 2023 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This review provides an overview of polycystic ovary syndrome, including its causes, symptoms, diagnosis, and treatment strategies, and reports no new research findings.
April 2023 in “Cancer research” This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.
January 2024 in “Animals” This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.
19 citations
,
March 2022 in “International Journal of Environmental Research and Public Health” This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.
70 citations
,
December 2008 in “Cancer Research” This study found that activating CXCR2 on ras-transformed keratinocytes promotes migration and tumor development in a mouse skin model.
December 2022 in “International journal of preventive, curative & community medicine” This article reviews current understanding and management strategies for polycystic ovary syndrome, emphasizing lifestyle changes alongside medical treatment, and reports no new clinical results.
26 citations
,
December 2020 in “Nature metabolism” Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.
46 citations
,
May 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses the state-of-the-art knowledge on pseudoxanthoma elasticum, summarizing recent advancements in genetics, pathomechanisms, and potential treatments but reports no new clinical findings.
2 citations
,
November 2019 in “Journal für Klinische Endokrinologie und Stoffwechsel” This review discusses the complex and variable presentation of polycystic ovary syndrome, emphasizing the need for consistent diagnostic criteria and individualized treatment strategies but reports no new clinical results.
9 citations
,
November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
January 2025 in “International Journal of Trichology” This study found that adding PRP to DPCP treatment for severe alopecia areata did not enhance effectiveness compared to DPCP alone.
October 2025 in “Cell Death and Disease” In this study, researchers developed two novel mouse models to investigate how CD271 deletion in keratinocytes affects skin homeostasis, finding that it leads to changes resembling dysplastic skin conditions with immune cell recruitment and inflammatory cytokine release.
10 citations
,
January 2018 in “Postępy Dermatologii i Alergologii” This study found that 21 out of 39 patients with alopecia areata experienced more than 50% hair regrowth after six months of DPCP treatment, with better outcomes observed in those treated at 3-week intervals compared to weekly intervals.
This study identified seven novel CYP17A1 inhibitor scaffolds as potential leads for treating polycystic ovary syndrome through an in silico approach, demonstrating favorable interactions, drug-like properties, and predicted bioactivities warranting further experimental validation.
This study found that while educating healthcare providers significantly improved their knowledge of polycystic ovarian syndrome, it did not lead to better diagnosis or management outcomes in a free clinic setting.
52 citations
,
May 1997 in “Journal of Biological Chemistry” This study suggests that polyamines regulate CK2 enzyme activity and its subcellular distribution, as demonstrated in mouse models and cell cultures with elevated levels of ornithine decarboxylase.
August 2020 in “Research Square (Research Square)” This study found that young females in Punjab, Pakistan, showed increased prevalence of PCOS symptoms, yet most were unaware of PCOS, suggesting a need for enhanced educational efforts.
April 2017 in “Journal of Investigative Dermatology” The researchers reported that iPSCs derived from Sendai virus reprogrammed blood cells can mature into functional keratinocytes for up to 60 days, potentially offering new approaches for DEB treatment.
March 2026 in “Anti-Aging Eastern Europe” This review examines current evidence on personalized management strategies for PCOS, but does not present new clinical results; the authors advocate for treatments tailored to predominant symptoms and individual health profiles.
1 citations
,
August 2024 in “Journal of Pharmacy & Pharmaceutical Sciences” This study found that forming inclusion complexes of DPCP with HPβCD using the 3D ground mixture method enhances its anti-inflammatory activity at lower doses compared to complexes with β-CD.
1 citations
,
November 2018 in “Dermatologic Therapy” This report describes the use of compounded topical preparations to treat two severe psoriasis patients and calls for further studies on their regulation, protocol, and stability evaluation.
April 2025 in “International Journal of Homoeopathic Sciences” This case report describes marked improvement in symptoms for a 24-year-old woman with PCOS following individualized homeopathic treatment, which reportedly included a reduction in irregular menstruation, vaginal discomfort, and weight gain.
January 2026 in “Scientific Reports” In this study, researchers identified 19 genetic risk loci and highlighted 16 candidate causal genes, including immune-related ones, associated with polycystic ovary syndrome, emphasizing the role of specific immune cells like T cells and NK cells in its pathogenesis.
This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.
August 2025 in “International Journal of Environmental Sciences” In this descriptive cross-sectional study, researchers observed that less than 10% of female nursing students in Dharmapuri have been diagnosed with polycystic ovarian syndrome, though many show increasing symptom prevalence and poor health-related behaviors, underlining the need for better education and regular gynecological check-ups.
June 2024 in “International Journal of Ayurveda and Pharma Research” In this study involving 40 PCOS patients, the authors observed notable improvements in menstrual cycle regularity and ovarian cyst volume reduction using Tila kashayam and Shatapuspa choornam treatments, though they reported no significant changes in hirsutism, BMI, or waist circumference over three months.
August 2024 in “Indian Journal Of Clinical Practice” A balanced diet and healthy lifestyle help manage PCOS symptoms.