2 citations,
May 2021 in “Research Square (Research Square)” Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
2 citations,
December 2019 in “Biomedical dermatology” Minoxidil works faster, but ketoconazole is a safer alternative for female hair loss.
1 citations,
February 2014 in “Analytical Letters” The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.
May 2023 in “Asian journal of research in pharmaceutical sciences” Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.
April 2021 in “Research Square (Research Square)” The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
45 citations,
May 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
89 citations,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
38 citations,
September 2006 in “Journal of Dermatological Science” Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.
28 citations,
December 2003 in “Medical Hypotheses” Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
9 citations,
June 2019 in “Mycopathologia” Malassezia yeast linked to hair loss; ketoconazole helps treat it.
9 citations,
January 2008 in “Medical mycology” A dog's skin infection caused by the fungus Chaetomium globosum was effectively treated with ketoconazole.
2 citations,
January 1983 in “Archives of Dermatology” A 3-year-old boy's scalp infection was treated with ketoconazole.
2 citations,
December 2017 in “PubMed” A long-term pubic rash was finally diagnosed as white piedra and cured with ketoconazole.
1 citations,
January 2022 in “Advances in animal and veterinary sciences” Ketoconazole cream effectively treats fungal skin infections in cats.
1 citations,
September 2016 in “Veterinary dermatology” A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
1 citations,
February 2014 in “Revista de investigaciones veterinarias del Perú” A pet rabbit had a skin infection that was cured with ketoconazole.
April 2021 in “Cermin Dunia Kedokteran” Two siblings with tinea capitis improved after treatment with ketoconazole.
December 2020 in “Jurnal RSMH Palembang (Online)” A man with a fungal scalp infection got better after treatment with griseofulvin, cetirizine, and ketoconazole shampoo.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.
15 citations,
January 2009 in “Indian journal of dermatology, venereology, and leprology” Scalp white piedra can be treated with oral itraconazole and topical ketoconazole.
125 citations,
May 2010 in “Pediatric dermatology” Systemic treatment is necessary for tinea capitis in children, with griseofulvin preferred for Microsporum infections.
121 citations,
January 1991 in “Acta dermato-venereologica” Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
90 citations,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
80 citations,
August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
78 citations,
October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
66 citations,
January 1987 in “Journal of Investigative Dermatology” Coal tar shampoo increases enzyme activity in hair follicles, enhancing carcinogen binding to DNA.
59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
55 citations,
July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.