October 2010 in “Epilepsy Currents” Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
2 citations,
December 2017 in “PubMed” A long-term pubic rash was finally diagnosed as white piedra and cured with ketoconazole.
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
15 citations,
January 2009 in “Indian journal of dermatology, venereology, and leprology” Scalp white piedra can be treated with oral itraconazole and topical ketoconazole.
March 2021 in “Clin-Alert” The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
184 citations,
August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
125 citations,
May 2010 in “Pediatric dermatology” Systemic treatment is necessary for tinea capitis in children, with griseofulvin preferred for Microsporum infections.
121 citations,
January 1991 in “Acta dermato-venereologica” Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
93 citations,
February 2008 in “Atmospheric environment” Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.
90 citations,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
82 citations,
January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
80 citations,
August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
78 citations,
September 2006 in “International Journal of Cosmetic Science” Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.
78 citations,
October 2003 in “Cochrane library” Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
66 citations,
June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
66 citations,
January 1987 in “Journal of Investigative Dermatology” Coal tar shampoo increases enzyme activity in hair follicles, enhancing carcinogen binding to DNA.
59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
58 citations,
June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
57 citations,
August 1998 in “The journal of small animal practice/Journal of small animal practice” Malassezia-associated dermatitis can cause itching in cats with feline paraneoplastic alopecia.
55 citations,
July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
55 citations,
December 1987 in “Archives of Dermatology” Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
38 citations,
July 2010 in “Clinical, cosmetic and investigational dermatology” To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.
36 citations,
June 2012 in “PubMed” There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
35 citations,
November 1996 in “Journal of the American Academy of Dermatology” Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
33 citations,
February 1996 in “Journal of The American Academy of Dermatology” Treat scalp and beard fungal infections early with oral antifungal medication and sometimes topical therapy, avoiding unnecessary allergy tests and surgery.
32 citations,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Most women preferred the 1% pyrithione zinc shampoo for better hair smoothness and less frizz while controlling dandruff.
32 citations,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
24 citations,
March 1998 in “Mycoses” Early diagnosis and effective treatment of kerion Celsi prevent scarring and permanent hair loss.