78 citations
,
October 2003 in “Cochrane library” This review found that adding cyproterone acetate to estradiol showed a subjective improvement in hirsutism versus placebo, but comparisons with other therapies revealed no clinical differences.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
66 citations
,
January 2000 in “Dermatology” This review discusses the nature, origin, and treatments of dandruff, with a focus on the role of *Malassezia* spp. and other triggering factors, but reports no new research findings.
66 citations
,
January 1987 in “Journal of Investigative Dermatology” This study found that enzyme activity critical to cancer induction by polycyclic aromatic hydrocarbons in human hair follicles increased after using a crude coal tar-containing shampoo for four days and was substantially inhibited by imidazole compounds.
59 citations
,
February 2003 in “Veterinary Dermatology” This narrative review discusses the use of cyclosporin for various skin diseases in small animals and notes minimal side effects at therapeutic doses, but reports no original clinical findings.
58 citations
,
June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.
57 citations
,
August 1998 in “The journal of small animal practice/Journal of small animal practice” This study reported that Malassezia-associated dermatitis can cause pruritus in cats with feline paraneoplastic alopecia.
55 citations
,
July 2013 in “Dermatologic therapy” This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.
55 citations
,
December 1987 in “Archives of Dermatology” This review discusses two genetic disorders affecting biotin metabolism, each resulting in distinctive skin and hair manifestations, and outlines the associated serious metabolic complications.
43 citations
,
January 1970 in “Acta Medica Scandinavica” This study found that obese patients experienced similar weight loss on a very low-calorie diet and total fast, but the diet was associated with fewer complications.
38 citations
,
July 2010 in “Clinical, cosmetic and investigational dermatology” This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.
36 citations
,
June 2012 in “PubMed” This review discusses various treatments for androgenetic alopecia, including minoxidil, finasteride, dutasteride, ketoconazole, and experimental options, but reports limited clinical trial evidence for efficacy.
35 citations
,
November 1996 in “Journal of the American Academy of Dermatology” This study reports two HIV-infected men with a rare M. canis infection unresponsive to ketoconazole and terbinafine, where itraconazole was effective but prolonged treatment led to only one cure.
33 citations
,
June 2007 in “International Journal of Pharmaceutics” This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.
33 citations
,
February 1996 in “Journal of The American Academy of Dermatology” Treat scalp and beard fungal infections early with oral antifungal medication and sometimes topical therapy, avoiding unnecessary allergy tests and surgery.
32 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Most women preferred the 1% pyrithione zinc shampoo for better hair smoothness and less frizz while controlling dandruff.
32 citations
,
November 1996 in “International Journal of Dermatology” This review discusses the use of antiandrogen therapy in dermatology, covering treatments for conditions like acne, hirsutism, and androgenic alopecia but reports no new clinical findings.
25 citations
,
January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
24 citations
,
July 2009 in “Mycoses” This case report describes an adult patient with tinea capitis due to Microsporum canis who experienced complete hair regrowth following treatment with fluconazole and ketoconazole shampoo.
24 citations
,
March 1998 in “Mycoses” In this study, 31 children with kerion Celsi were treated successfully with antifungal medications, emphasizing the importance of early diagnosis and treatment to prevent scarring and hair loss.
22 citations
,
January 2009 in “Medical mycology” In this case report, researchers identified Arthroderma vanbreuseghemii as the cause of a familial fungal infection, which was successfully treated with itraconazole and topical terbinafine cream.
21 citations
,
January 2008 in “Journal of Pediatric Endocrinology and Metabolism” This study found that combined treatment with anastrozole and cyproterone acetate improved the adult height prognosis in testotoxicosis, as observed in two brothers, with good tolerance reported.
20 citations
,
February 2016 in “American Journal of Pathology” This study indicates that the OVOL1-OVOL2 axis may play a significant role in hair follicle differentiation and growth, potentially serving as therapeutic targets for hair disorders like alopecia and in the tumorigenesis of pilomatricoma.
18 citations
,
November 1989 in “Clinical and experimental dermatology” This case report describes a 5-year-old girl with an extensive Microsporum canis scalp infection, highlighting griseofulvin as the preferred treatment and noting corticosteroids' benefit in severe inflammatory cases.
17 citations
,
October 2001 in “Veterinary dermatology” This case report indicates that epidermal dysplasia in two West Highland White Terriers might be caused by a reaction to Malassezia infection or self-trauma, rather than being congenital.
15 citations
,
March 2019 in “Veterinary Dermatology” This study found that three mousse products containing chlorhexidine and varying antifungal components maintained significant antibacterial activity against S. pseudintermedius in vitro for up to 10 days, while other mousses did not show significant differences.
14 citations
,
September 2015 in “Expert Opinion on Therapeutic Targets” This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.
14 citations
,
July 2009 in “Current Opinion in Otolaryngology & Head and Neck Surgery” This review discusses recent developments in hair restoration, highlighting the continued prominence of follicular unit strip surgery and the growing literature on the relatively new technique of follicular unit extraction, without presenting new clinical results.
13 citations
,
December 2012 in “Medical mycology case reports” In this case report, an atypical form of tinea favosa in an 11-year-old girl was initially misdiagnosed, highlighting the importance of mycological examination for accurate diagnosis, especially when diffuse scalp scaling is present.
12 citations
,
August 2016 in “Mycopathologia” This case study reports a 36-year-old man's fungal infection, identified as Trichosporon inkin, which was treated with shaving and antifungal therapy.