11 citations
,
June 2016 in “European Journal of Medicinal Chemistry” This study found that two synthesized androst-4-ene-3-one derivatives, 6f and 6g, exhibited stronger anti-proliferative effects than common drugs on prostate cancer cell lines, with low toxicity to rat cells.
11 citations
,
December 2014 in “Clinical Obstetrics and Gynecology” This article presents a systematic approach for obstetricians/gynecologists to diagnose and manage common types of nonscarring hair loss in women, reporting no new clinical results.
11 citations
,
January 1998 in “Dermatology” This review explores various substances with potential antiandrogenic effects for treating acne, highlighting evidence for isotretinoin, and discusses the future consideration of 5 alpha-reductase inhibitors as antiandrogens.
10 citations
,
January 2013 in “International journal of trichology” This article describes a rare case of mixed black and white piedra in a patient's scalp hair, which is unusual as these two types of piedra rarely occur together.
This pilot study found that a novel regimen including NuH Hair led to significant hair growth in male patients with androgenic alopecia, regardless of atopy status, with quicker results when additional treatment components were used.
10 citations
,
January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
9 citations
,
June 2019 in “Mycopathologia” This study found that the presence of Malassezia fungi in the scalp's hairy roots was more pronounced in individuals with androgenetic alopecia than in healthy controls, suggesting a potential link to the condition.
9 citations
,
October 2013 in “Pediatric dermatology” This study highlights a dissecting cellulitis-like presentation of tinea capitis in children that should be identified to ensure correct diagnosis and treatment to prevent scarring alopecia.
9 citations
,
January 2008 in “Medical mycology” In this study, ketoconazole treatment successfully cured a dog with erythematous epilation caused by Chaetomium globosum, with new hair growth observed 9 weeks later.
9 citations
,
April 1987 in “International Journal of Dermatology” This article reviews rosacea and rosacea-like demodicidosis, discussing historical findings, but provides no new clinical results; the authors highlight the role of Demodex in related skin conditions.
9 citations
,
January 1983 in “Journal of Chromatography B Biomedical Sciences and Applications” This study found that enzyme activity related to cancer induction by polycyclic aromatic hydrocarbons can be increased by using a shampoo containing crude coal tar and significantly inhibited by imidazole compounds in human hair follicles.
8 citations
,
June 2018 in “ACTA SCIENTIAE VETERINARIAE” This report describes the first diagnosed case of dermatophytosis caused by Microsporum canis in a young maned wolf, emphasizing the importance of monitoring emerging diseases in this vulnerable species.
8 citations
,
April 2015 in “British Journal of Dermatology” This report describes two cases of white piedra caused by Trichosporon inkin in a northern climate, detailing clinical findings and diagnosis without presenting new experimental results.
8 citations
,
March 2010 in “Chinese medical journal/Chinese Medical Journal” This study found that antifungal therapy significantly reduced pustules in patients with refractory acne, indicating a potential role for Malassezia infection in such cases.
8 citations
,
October 1989 in “International Journal of Dermatology” This review discusses the role of Cytochrome P-450 in dermatology and reports no new clinical results.
7 citations
,
December 2019 in “American Journal of Clinical Dermatology” This review discusses the potential efficacy of topical antiandrogen therapies for treating androgenetic alopecia and acne vulgaris, finding promising results but highlighting the need for more comprehensive studies.
7 citations
,
September 2013 in “Current Dermatology Reports” This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.
6 citations
,
August 2009 in “Mini-reviews in Medicinal Chemistry” This review summarizes the structural and chemical characteristics of current and novel antiandrogenic drugs but reports no new clinical findings.
6 citations
,
October 1998 in “PubMed” This case study reports a new variant of chronic dermatophytosis with giant cutaneous horns, suggesting a possible genetic link and highlighting successful treatment with antifungal medications.
5 citations
,
March 2023 in “Journal of the American Academy of Dermatology” This study reports that prurigo pigmentosa did not appear linked to a specific common trigger such as the ketogenic diet, but suggests that oral antibiotics might effectively resolve the condition.
5 citations
,
January 2020 in “Veterinary Dermatology” In this study, researchers evaluated the antifungal effectiveness of topical products on infected kitten hair, finding most were effective after one application, with enilconazole and lime sulfur showing residual activity; however, 0.15% ketoconazole with chlorhexidine had no such lasting effect.
5 citations
,
January 2018 This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.
4 citations
,
January 2018 in “Indian dermatology online journal” This case report found that dermoscopy, showing characteristic "comma" and "corkscrew" hairs, effectively identified tinea capitis in a 7-year-old girl, allowing for early treatment before confirmation with fungal culture.
3 citations
,
April 2021 in “Berkala ilmu kedokteran/Journal of the medical sciences” This report describes a case of tinea capitis caused by Epidermophyton floccosum, highlighting its unusual ability to perforate hair and act as an etiological agent for the condition.
3 citations
,
January 2021 in “Therapeutic advances in infectious disease” This report describes a 9-year-old girl with a scalp kerion treated successfully with terbinafine and ketoconazole shampoo, leading to hair regrowth after two months.
3 citations
,
January 2020 in “Acta veterinaria indonesiana” In this case study, a Persian cat with dermatophytosis showed a reduction in skin lesions after being treated with oral itraconazole and topical ketoconazole.
3 citations
,
February 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This case report details a 73-year-old woman with systemic sarcoidosis, whose scalp biopsy revealed features consistent with both sarcoidosis and frontal fibrosing alopecia, emphasizing the necessity of biopsy in complex alopecia diagnoses.
3 citations
,
January 2015 in “Journal of clinical and diagnostic research” This case report described a seven-year-old with tinea capitis, which improved clinically after six weeks of griseofulvin treatment, changing the fungal strain from Trichophyton violaceum white variant to violet strain.
3 citations
,
August 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review discusses various therapeutic options for female pattern hair loss but reports no new clinical results, focusing on the challenges and limitations of current treatments like minoxidil and finasteride.
3 citations
,
October 2010 in “Epilepsy Currents” This study found that when metabolism changes and extracellular glucose decreases, hippocampal CA3 neurons release ATP, which is converted to adenosine and reduces neuron excitability, enhancing the seizure threshold.