TLDR Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.
Tinea capitis in men, including those with HIV, was rare, and Microsporum species nail infections were extremely rare. This study described two HIV-infected men with unusual M. canis infections. One presented with alopecia and the other with scalp scaling; one also had tinea unguium. Ketoconazole and terbinafine were ineffective, but itraconazole was effective after many months, curing only one patient.
10 citations
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May 1991 in “Journal of the American Academy of Dermatology” 84 citations
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January 1987 in “The Pediatric Infectious Disease Journal” The study examined 80 children with tinea capitis to understand its epidemiology and compare the effectiveness of griseofulvin and ketoconazole treatments. The majority of infections were caused by Trichophyton tonsurans (74%). Griseofulvin proved more effective, with a shorter mean time to achieve a sterile culture (4 weeks) compared to ketoconazole (8 weeks), and a quicker complete scalp clearing (median 60 days versus 108 days for ketoconazole). The study highlighted griseofulvin's superior efficacy in treating tinea capitis in children.
January 2022 in “International Journal of Research Publications” Griseofulvin effectively treats tinea capitis caused by Microsporum canis.
