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    Glossary Keratoacanthoma

    rapidly growing skin bump resembling a small volcano

    Keratoacanthoma is a type of skin growth that resembles a small, volcano-like bump with a central crater filled with keratin, a protein found in hair and nails. It typically grows rapidly over a few weeks to months and often appears on sun-exposed areas of the skin, such as the face, arms, and hands. While it is generally considered benign, it can sometimes be difficult to distinguish from squamous cell carcinoma, a type of skin cancer, so medical evaluation and possibly a biopsy are recommended.

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    Research 30 of 177

    1. The keratoacanthoma: A review Journal of Surgical Oncology · 1979 · 80 citations
    2. Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk Nature Communications · 2014 · 51 citations
    3. Keratoacanthoma and other types of squamous cell carcinoma with crateriform architecture: Classification and identification The Journal of Dermatology · 2013 · 45 citations
    4. The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15 Journal of Cutaneous Pathology · 2014 · 28 citations
    5. Intralesional therapy for the treatment of keratoacanthoma Dermatologic therapy · 2019 · 25 citations
    6. Histogenesis of keratoacanthoma: histochemical and immunohistochemical study Oral surgery, oral medicine, oral pathology and oral radiology · 2014 · 16 citations
    7. Keratoacanthoma of the lip: A case report with emphasis on histogenesis Journal of Oral and Maxillofacial Pathology · 2017 · 8 citations
    8. A rare case of multiple keratoacanthomas treated with oral acitretin and intralesional methotrexate Indian dermatology online journal · 2016 · 5 citations
    9. Role of the Wnt signaling pathway in keratoacanthoma Cancer reports · 2019 · 2 citations
    10. IMMUNOHISTOCHEMICAL EXPRESSION OF KERATIN PROTEINS IN KERATOACANTHOMAS OF THE SKIN Oncology Reports · 1994 · 2 citations
    11. CLINICAL-MORPHOLOGICAL FEATURES AND NEW ASPECTS OF KERATOACANTHOMA TREATMENT:NARRATIVE REVIEW BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY · 2026
    12. Solitary Keratoacanthoma of the Scalp: A Case Report Curēus · 2023
    13. Cytologic Aspect of Keratoacanthoma with Granulomatous Inflammation in a Dog Journal of Veterinary Clinics · 2009
    14. Hair sheath keratins in follicular tumors. (5). Identification of hair sheath keratins in keratoacanthoma; Histopathological hair sheath structures in the tumor and their significance as differential histopathological criteria from squamous cell carcinoma. The Nishinihon Journal of Dermatology · 1990
    15. 43853 Case of Reactive Keratoacanthomas arising Eight Years After Multicolored Tattoo Placement Journal of the American Academy of Dermatology · 2023
    16. Giant Keratoacanthoma Mimicking Squamous Cell Carcinomain a Patient with Chronic Myeloid Leukemia Dermatology Review · 2025
    17. 129 Genetic transformation of keratoacanthoma-type cutaneous squamous cell carcinoma following intralesional chemotherapy Journal of Investigative Dermatology · 2018 · 2 citations
    18. p63 expression in normal skin and usual cutaneous carcinomas Journal of Cutaneous Pathology · 2002 · 157 citations
    19. Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin Carcinogenesis · 1998 · 88 citations
    20. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    21. Cutaneous adverse effects of BRAF inhibitors in metastatic malignant melanoma, a prospective study in 20 patients. Journal of the European Academy of Dermatology and Venereology · 2014 · 31 citations
    22. Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy Seminars in Cutaneous Medicine and Surgery · 1996 · 18 citations
    23. Prospective Case Series of Cutaneous Adverse Effects Associated With Dabrafenib and Trametinib Journal of cutaneous medicine and surgery · 2016 · 10 citations
    24. Controversial Concepts The American Journal of Dermatopathology · 2013 · 5 citations
    25. Correction: RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 4 citations
    26. Perspectives on Dermatopathology Archives of Dermatology · 1976 · 1 citations
    27. Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients 2023
    28. Trichofolliculoma on gluteal area: A unique case report TURKDERM · 2022
    29. Rapidly growing hand nodule The Journal of Family Practice · 2021
    30. Tricholemmoma and tricholemmal carcinoma and Cowden syndrome 2019