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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

A 55-year-old woman with several health conditions did not see hair regrowth after a transplant.

m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

Found new possible treatments for hair loss.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

Thyroid function affects skin health, with a complex interaction between the two.

Mice with human skin protein K8 had more skin problems and cancer.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.

Loose Anagen Syndrome is a hair condition where hairs can be easily pulled out, mainly affecting young girls, and may improve on its own or with treatment.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.