Genetic Susceptibility to Alopecia

    February 2019 in “ The New England Journal of Medicine ”
    Jouni Uitto
    Studysummary This article discusses the composition and function of the dermal papilla in hair follicles, focusing on its role in hair shaft generation and suggesting that cell loss in this area may contribute to hair loss.
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    Research cited in this study 8

    1. Variant PADI3 in Central Centrifugal Cicatricial Alopecia The New England Journal of Medicine · 2019
    2. Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia Journal of The American Academy of Dermatology · 2018
    3. Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias Experimental Dermatology · 2018
    4. Central Centrifugal Cicatricial Alopecia: New Insights and a Call for Action Journal of Investigative Dermatology Symposium Proceedings · 2017
    5. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome American journal of human genetics · 2016
    6. Updates in the Understanding and Treatments of Skin and Hair Disorders in Women of Color International Journal of Women's Dermatology · 2015
    7. Ethnic Hair Disorders: Diagnosis and Management Current problems in dermatology · 2015
    8. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014

    Related research 8

    1. Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods Skin Pharmacology and Physiology · 2020
    2. Genetic Susceptibility to Alopecia The New England Journal of Medicine · 2019
    3. Hair Follicle Generation by Injections of Adult Human Follicular Epithelial and Dermal Papilla Cells into Nude Mice PubMed · 2017
    4. Hair Physiology: Hair Growth, Alopecia, Scalp Treatment, Etc. Elsevier eBooks · 2017
    5. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    6. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998
    7. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988
    8. The Dermal Papilla and Maintenance of Hair Growth 1988