12 citations,
December 2011 in “Journal of Dermatological Science” The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.
23 citations,
September 2015 in “International Journal of Molecular Medicine” Activating ER-β, not ER-α, improves skin cell growth and wound healing.
3 citations,
June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
5 citations,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
115 citations,
August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
40 citations,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
July 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists found new and known long non-coding RNAs in mouse hair follicle stem cells that may be important for stem cell function and could be targets for cancer treatment.
3 citations,
May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
April 2018 in “Journal of Investigative Dermatology” The human skin's outer layer has more variety in cell types and development paths than previously thought.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
1 citations,
October 2022 in “Bioengineering” Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
7 citations,
June 2021 in “JAAD Case Reports” A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.
1 citations,
May 2023 in “Journal of molecular evolution” Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
April 2023 in “Journal of Investigative Dermatology” Type 2 cytokines IL-4 and IL-13 increase skin's vulnerability to Staphylococcus aureus, which could be important for treating atopic dermatitis.
92 citations,
September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
8 citations,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
111 citations,
November 2007 in “Clinics in Dermatology” Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.
28 citations,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
20 citations,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
7 citations,
March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
42 citations,
March 2010 in “Endocrinology” Mice with human gene experienced hair loss when treated with DHT.
19 citations,
April 2015 in “International Journal of Molecular Sciences” The research identified genes and pathways important for sheep wool growth and shedding.
39 citations,
January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
4 citations,
December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
September 2023 in “Cells tissues organs” Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
January 2023 in “Figshare” Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
2 citations,
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Autophagy changes the protein makeup of hair.
2 citations,
November 1992 in “Journal of dermatology” Hair cells grown in a lab showed specific hair proteins.