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    Did you mean Keratin 85?
    Glossary Keratin 85

    protein crucial for hair structure and strength

    Keratin 85, also known as KRT85, is a type of protein found in hair follicles. It plays a crucial role in the structure and strength of hair, contributing to its resilience and elasticity. Mutations in the KRT85 gene can lead to hair disorders, such as monilethrix, which is characterized by beaded or fragile hair.

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    1. Dynamics of Merkel Cell Patterns in Developing Hair Follicles in the Dorsal Skin of Mice, Demonstrated by a Monoclonal Antibody to Mouse Keratin 8 Cells Tissues Organs · 1995 · 64 citations
    2. Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia 2009 · 42 citations
    3. Immunohistochemical demonstration of keratins 8 and 14 in benign tumours of the skin appendage Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 1991 · 38 citations
    4. Structural behavior of keratin-associated protein 8.1 in human hair as revealed by a monoclonal antibody Journal of Structural Biology · 2018 · 3 citations
    5. Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity Advanced Science · 2023
    6. Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene on Fibre Traits in Inner Mongolia Cashmere Goats Asian-Australasian Journal of Animal Sciences · 2007 · 20 citations
    7. Study on kerantin association protein 8.1 gene expression of Liaoning cashere goats in skin and hair follicle China Feed · 2014
    8. Study on Differential Expression of Keratin Associated Protein 8-1 Gene of Different Varieties of Ovis aries in Skin and Hair Follicle China Animal Husbandry & Veterinary Medicine · 2014
    9. Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin and the phorbol ester 12-<i>O</i>-tetradecanoylphorbol-13-acetate Carcinogenesis · 1987 · 12 citations
    10. The Hairless Phenotype of the Hirosaki Hairless Rat Is Due to the Deletion of an 80-kb Genomic DNA Containing Five Basic Keratin Genes Journal of Biological Chemistry · 2008 · 35 citations
    11. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Affects Keratin 1 and Keratin 17 Gene Expression and Differentially Induces Keratinization in Hairless Mouse Skin Journal of Investigative Dermatology · 1997 · 45 citations
    12. Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice The FASEB Journal · 2004 · 49 citations
    13. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair (vol 8, pg 241, 2008) 2009
    14. [An immunohistochemical study on the normal human anagen hair and hair follicle using anti-hair keratin monoclonal antibodies (HKN-5, HKN-6, HKN-7 and HKN-8)]. PubMed · 1985
    15. Keratin expression in basal cell carcinomas British Journal of Dermatology · 1992 · 128 citations
    16. Keratins and skin disease 2015 · 69 citations
    17. Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice Journal of Biological Chemistry · 2014 · 15 citations
    18. Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family Journal of Investigative Dermatology · 2013 · 11 citations
    19. iTRAQ-based quantitative proteomics revealing the therapeutic mechanism of a medicinal and edible formula YH0618 in reducing doxorubicin-induced alopecia by targeting keratins and TGF-β/Smad3 pathway Heliyon · 2024
    20. 583 Promoting hair growth and hair keratin production with a propolis extract Journal of Investigative Dermatology · 2024
    21. Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family 2002 · 48 citations
    22. Monilethrix in monozygotic twins with very rare mutation in KRT 86 gene Journal of the European Academy of Dermatology and Venereology · 2017 · 6 citations
    23. 895 Isoproterenol directs human hair follicle-associated pluripotent (hHAP) stem cells to differentiate to cardiac muscle cells 2017
    24. 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle Journal of Investigative Dermatology · 2017
    25. 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision Journal of Investigative Dermatology · 2017
    26. 837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy Journal of Investigative Dermatology · 2017
    27. 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium Journal of Investigative Dermatology · 2017
    28. Nestin expression in hair follicle sheath progenitor cells Proceedings of the National Academy of Sciences · 2003 · 352 citations
    29. Ectopic<i>Atoh1</i>expression drives Merkel cell production in embryonic, postnatal and adult epidermis Development · 2015 · 41 citations
    30. Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology British Journal of Dermatology · 2012 · 33 citations