Search

for
Search:

Did you mean Keratin 35?

Glossary Keratin 35

protein crucial for hair and nail structure and strength

Keratin 35 (KRT35) is a type of protein found in the hair and nails, playing a crucial role in their structure and strength. It is part of the keratin family, which are fibrous structural proteins essential for the mechanical integrity and protective functions of epithelial cells.

Related Terms

Sort by

Research

30 / 1000+ results

research Expression analysis of the type I keratin protein keratin 33A in goat coat hair

8 citations , July 2011 in “Animal science journal”

The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.

iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway

research iTRAQ-based quantitative proteomics revealing the therapeutic mechanism of a medicinal and edible formula YH0618 in reducing doxorubicin-induced alopecia by targeting keratins and TGF-β/Smad3 pathway

June 2024 in “Heliyon”

This animal study found that YH0618 may alleviate doxorubicin-induced alopecia and affects proteins like keratin and Smad3, suggesting potential therapeutic targets. The researchers analyzed protein expression changes to understand YH0618's effects in treating chemotherapy-related hair loss.

Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in Mouse Skin

research Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in the Mouse Skin

11 citations , January 2015 in “Skin pharmacology and physiology”

In this study, oral collagen peptides increased certain gene expressions related to epidermis development and the hair cycle in hairless mice skin, suggesting potential links to hair health.

research The human keratins: biology and pathology

1398 citations , May 2008 in “Histochemistry and Cell Biology”

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

87 citations , July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

research Association analysis of polymorphisms in six keratin genes with wool traits in sheep

17 citations , November 2017 in “Asian-Australasian journal of animal sciences”

This study found that mutations in certain keratin genes significantly affect wool traits in Chinese Merino sheep, suggesting these genes could be important for sheep breeding to improve wool quality.

research Homo- and heteropolymer self-assembly of recombinant trichocytic keratins

13 citations , July 2017 in “Biopolymers”

This study presents recombinant human hair keratins K31 and K81, observing novel nanostructures from their self-assembly and emphasizing disulfide crosslinking's role in this process.

research In vitro Assembly Properties of Human Type I and II Hair Keratins

12 citations , January 2014 in “Cell structure and function”

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

research Understanding the biochemical properties of human hair keratins : self-assembly potential and cell response

January 2020

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption

research pH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption

7 citations , February 1998 in “Polymer journal”

This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.

White Adipose Tissue Initiates IL-33-Dependent Expression of Interleukin 4/13 in Myeloid Cells During Inflammation

research Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung

August 2024 in “Qucosa (Saxon State and University Library Dresden)”

In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.

research IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia

March 2023 in “Clinical, cosmetic and investigational dermatology”

This study suggests that IL-33 promotes hair follicle changes and T cell infiltration in psoriatic mice and humans, contributing to psoriatic alopecia.

research Mechanical and biological properties of keratose biomaterials

140 citations , August 2011 in “Biomaterials”

This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.

research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine

30 citations , March 2017 in “ACS biomaterials science & engineering”

This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.

research Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production

22 citations , April 2020 in “Scientific reports”

This study explored gene expression in Changthangi goats and found that higher expression of keratin-related genes and specific signaling pathways may play a role in the development of Pashmina fiber.

research The proteomic profile of hair damage

20 citations , June 2012 in “British Journal of Dermatology”

This study discusses the proteomic profile associated with hair damage but does not report new experimental findings.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

This study found that inhibiting AP1 transcription factor activity in the suprabasal epidermis of mice alters keratinocyte gene expression, reducing barrier integrity and mimicking human keratoderma.

research Recent advances in preparation and biomedical applications of keratin based biomaterials

9 citations , November 2024 in “Biotechnology for Sustainable Materials”

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

research Identification of the key proteins associated with different hair types in sheep and goats

2 citations , September 2022 in “Frontiers in genetics”

This study found that cashmere has a significantly smaller mean fiber diameter compared to sheep and goat wool, and identified key proteins that may influence this difference.

research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer

December 2023 in “The journal of physical chemistry. B (1997 : Online)”

This study explored the potential of human hair keratin as a filtration material, finding that it may effectively absorb the pollutants diclofenac and perfluorobutanesulfonate. The researchers reported significant binding affinities through molecular simulations, supporting further investigation into keratin's use for water purification.

research Hair Keratin

7 citations , January 1990

research Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses

23 citations , November 2001 in “Archives of Dermatology”

This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.

research Generation of iPS-derived model cells for the analysis of hair development

April 2017 in “Journal of dermatological science”

In this study, researchers developed a model using iPS-derived cells to trace and evaluate hair follicle differentiation, which could aid in the development of hair growth treatments.

research Zoonotic Potential of Dermatophytosis in Small Mammals

15 citations , July 2015 in “Journal of exotic pet medicine”

This review discusses the prevalence, diagnosis, treatment, and prevention of zoophilic dermatophyte infections in small exotic mammals and reports no new clinical findings; it emphasizes the need for veterinary guidance and public awareness.

research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation

68 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.

research Disorders of Keratinization

44 citations , January 2004 in “American journal of clinical dermatology”

This review covers various disorders of cornification and their treatments, offering clinical insights but reporting no new research findings.

research Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation

35 citations , August 2009 in “Differentiation”

This study found that transcription factors HOXC13, LEF1, and FOXN1 repress DSG4 transcription, with the Notch pathway possibly involved in maintaining DSG4 expression in hair follicles.

Correlation and Regression Analysis of the KRT27 and ELOVL4 Genes in Cashmere Fineness and Other Production Performances in Liaoning Cashmere Goats

research Correlation and regression analysis of the KRT27 and ELOVL4 genes in cashmere fineness and other production performances in Liaoning cashmere goats

February 2025 in “Archives animal breeding/Archiv für Tierzucht”

This study found that certain gene polymorphisms in keratin 27 and ELOVL4 are linked to improved cashmere fineness and production traits in Liaoning cashmere goats.

research Genetics of Wool and Cashmere Fibre: Progress, Challenges, and Future Research

10 citations , November 2024 in “Animals”

This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.

research Integration Analysis of Hair Follicle Transcriptome and Proteome Reveals the Mechanisms Regulating Wool Fiber Diameter in Angora Rabbits

March 2024 in “International journal of molecular sciences”

In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.