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This review discusses the potential benefits and biological activities of MSC secretome for various skin applications, but it reports no new clinical results.

This review synthesizes current research on PPAR-γ signaling in hair follicle biology and its potential role in treating hair growth disorders like scarring alopecia and hirsutism, but reports no new clinical results.

This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.

This study highlights multiple factors contributing to hair graying, such as oxidative damage, melanocyte changes, and genetic influences, and suggests that repigmentation may be temporarily reversible, offering potential targets for future treatments while urging caution when applying mouse model findings to humans.

This study suggests that erlotinib exacerbates inflammation in a mouse model of skin disease and that IL-1 inhibition could mitigate skin-related side effects of EGFR inhibitors.

This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.

In this study, a patient with clinically amyopathic dermatomyositis experienced persistent skin issues despite treatment, highlighting questions about type I interferon's role in skin disorders and potential IFN-targeted therapies for cutaneous lupus erythematosus and dermatomyositis.

This review highlights the critical role of neuroregulation in skin wound healing, emphasizing how neurotransmitters and neuropeptides regulate inflammation, angiogenesis, and cell proliferation, and discusses potential therapeutic strategies, such as neuromodulation, to enhance these processes.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

This review discusses the mechanisms of skin-associated cell death and their potential role in treating inflammatory skin diseases, but presents no new clinical findings.

This review discusses the role of telomere length dynamics in hair follicle biology and reports no new clinical findings, emphasizing the need for further research in humans.

This study found that Alpinetin, applied topically in C57BL/6J mice, promoted hair regeneration by activating hair follicle stem cells through Wnt signaling, extending the anagen phase and increasing hair shaft length, with no cytotoxicity observed in keratinocytes and fibroblasts.

In this study, 21.1% of participants had actinic keratoses, with higher prevalence in men, and certain genetic and photoaging factors were positively associated with AK, though smoking was linked to reduced risk.

This review discusses recent advancements and ongoing challenges in engineering human skin with appendages using scaffold-free and scaffold-based bioengineering approaches, but it reports no new clinical results.

This review discusses the pathogenesis of melasma, including genetic, environmental, and hormonal factors, and highlights potential avenues for new treatments and preventive strategies, but reports no new experimental findings.

In this study, researchers found that Sox9 is critical for determining whether Nestin⁺ stem cells in adult mouse skin develop into melanocytes or glial cells, offering insights into possible paths for melanoma research.

In this study, researchers found that disrupting EGFR signaling in mice led to increased inflammation and hair follicle damage but that inhibiting the JAK-STAT1 pathway could restore hair growth and skin function.

This study demonstrated that human skin can be efficiently reinnervated using human induced pluripotent stem cell-derived neural stem cells, promoting skin vitality and sensory reinnervation comparable to physiological conditions.

This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.

This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.

This review explores the immunological aspects of epidermal differentiation in loricrin knockout mice, offering insights into keratinization and potential intrinsic factors affecting immune function, but provides no new clinical findings.

This review discusses how dental pulp stem cells and their derivatives may accelerate skin wound healing by modulating inflammation, promoting angiogenesis, optimizing extracellular matrix structure, and enhancing tissue formation, with implications for translating these findings into therapies for skin and mucosal repair.

This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.

Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

This study explores the regulatory effects of ursolic acid on macrophage function and suggests potential for developing new anti-inflammatory and immunomodulatory drugs, though further research is needed for clinical applications.

This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.

This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.

In this study, miR-221 was identified as a key factor in androgenetic alopecia pathogenesis due to its role in suppressing hair growth by interacting with androgen receptors and affecting related pathways.

This review discusses how targeting apoptosis pathways in hair and skin cells can inform the development of novel therapies, but it reports no clinical findings.

This review synthesizes existing research on the multilayered defense system of the skin, highlighting how physical, chemical, immune, and microbial barriers work together to maintain skin health, with disruptions in one often leading to broader barrier dysfunctions.