This study identified new geometric and mechanical parameters for curly and kinky/coily hair, which may inform more effective personal care products tailored to these hair types.
25 citations
,
March 2019 in “Dermatologic therapy” This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
3 citations
,
October 2024 in “Animals” This study identified three genes in the ovine KAP13 family on chromosome 1 and found that a specific allele of KRTAP13-2 is associated with improved wool fibre diameter uniformity in Chinese Tan sheep, suggesting its potential use as a marker for enhancing wool traits.
22 citations
,
August 2010 in “Annals of Plastic Surgery” This study suggests that reconstructive methods for burn alopecia should be tailored to the conditions of the scarring, with scalp extension and expansion recommended only for large, poor-quality alopecia due to a high complication rate.
February 2025 in “Archives animal breeding/Archiv für Tierzucht” This study found that certain gene polymorphisms in keratin 27 and ELOVL4 are linked to improved cashmere fineness and production traits in Liaoning cashmere goats.
1 citations
,
December 2025 in “Scientific Reports” In this study, researchers developed a predictive model for the onset of alopecia areata by analyzing six datasets to identify key feature genes and employing various machine learning algorithms, ultimately finding the XGBoost model most effective for clinical application.
10 citations
,
January 1971 in “The American midland naturalist” A simple method can show hair's surface pattern.
48 citations
,
June 2000 in “Japanese Journal of Cancer Research” This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study shows that IKZF1 and the protein IKAROS may play a role in the development of alopecia areata, based on findings from both mouse models and human scalp tissues.
12 citations
,
October 2018 in “Biotechnology reports” In this study, researchers reported that the application of refolded human K31 keratin protein significantly improved diameter, mechanical strength, and smoothness of chemically damaged hair after a single treatment.
16 citations
,
May 2023 in “Journal of the American Statistical Association” This study applied a novel Cox regression subsampling method to massive datasets, demonstrated using UK-biobank colorectal cancer data, effectively reducing computation time and memory usage while building a risk-prediction model under certain conditions involving right-censored and potentially left-truncated data with rare events.
November 2023 in “Journal of Dermatological Science” A new computer tool quickly measures hair thickness differences in people with common types of hair loss.
In this case study, a 36-year-old male with symptoms of keratosis pilaris atrophicans faciei and frontal fibrosing alopecia tested negative for a specific mutation, highlighting genetic testing's potential to improve diagnosis and treatment outcomes in these similar conditions.
September 2024 in “Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi” In this study, the XGBoost algorithm successfully diagnosed polycystic ovary syndrome with an accuracy of 0.87 using a dataset from Kerala, suggesting its usefulness for classification problems in healthcare.
44 citations
,
August 1990 in “PubMed” This study provides evidence for K1 and K10 derivatives' presence in the inner root sheath and hair cuticle, suggesting that these hair follicle parts may follow familiar keratinization principles.
20 citations
,
August 2017 in “PLoS ONE” This study identified and updated the annotation of 61 keratin genes in dogs and horses, improving the genome annotation in these species through RNA-seq data comparison.
12 citations
,
September 2012 in “Computer Graphics Forum” This study developed a method that combines image-based and simulation techniques to improve the reconstruction of hair dynamics from multi-view videos, enabling accurate hair motion representation and animation.
4 citations
,
December 1995 in “Anthropologischer Anzeiger” This study reports that electrophoretic patterns of hair keratins are more similar among family members than unrelated individuals, potentially aiding genetic studies.
40 citations
,
September 2010 in “Journal of Biological Chemistry” This study found that keratin K80, structurally similar to hair keratins, is broadly expressed in various epithelial tissues and is involved in intermediate filament formation with multiple type I partners.
95 citations
,
October 2007 in “International Journal of Dermatology” This study found that human hair can be classified into eight main types based on objective measurements of shape, rather than ethnic categories, enhancing the understanding of hair diversity globally.
22 citations
,
November 2014 in “Proteins Structure Function and Bioinformatics” In this study, researchers mapped cysteine accessibility in wool keratins and KAPs, revealing that certain cysteines in keratin end domains and Types I and II rod domains are accessible and likely involved in forming disulfide bonds.
2 citations
,
January 2024 in “IEEE Access” This study introduces AlopeciaDet, a novel feature fusion technique, using camera images to detect Alopecia Areata with 99.45% accuracy, outperforming existing methods by leveraging CRSHOG and ResNet-50 features.
34 citations
,
January 2016 in “Analytical Chemistry” This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.
March 2026 in “Mendeley Data” This tool was developed to enhance reproducibility and sensitivity in measuring partial hair regrowth in alopecia areata patients, particularly those undergoing JAK inhibitor therapy, using scalp photographs.
January 1990 in “The Nishinihon Journal of Dermatology” This study suggests that keratoacanthomas may be distinguished from squamous cell carcinoma by identifying hair follicle structures, based on keratin expression and histological features observed in tumor samples.
15 citations
,
January 1993 in “DNA sequence” This study sequenced a related gene to KRT2.9 called KRT2.13, which encodes a type II keratin protein not expressed in the hair follicle, and found significant sequence homology suggesting possible gene conversion or conservation of functional sequences.
10 citations
,
November 2024 in “Animals” This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.
14 citations
,
April 2016 in “PloS one” This study found that the promoter region of the sheep KRTAP11-1 gene drives specific transcriptional activity in wool follicles, suggesting it may regulate hair keratinocyte specificity.
August 2024 in “Advanced Healthcare Materials” In this study, water-soluble recombinant keratins, specifically RK81, were developed and used in microneedles to investigate their effect on hair growth, discovering that more than 40% of the hair follicles responded, demonstrating the potential for hair growth promotion.
1 citations
,
February 2018 in “Plastic and Aesthetic Research” This article describes a new instrument, the KD spreader, designed to help novice physicians perform follicular unit extraction hair transplantation with reduced trauma and operator fatigue, but it does not report new clinical results.