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The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

sPLA2-X is crucial for normal hair growth and follicle health.

Adipokines affect skin health and could be targeted for treating skin diseases.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.