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This study found that acne inversa is primarily an epithelial-driven disease, with cyst-forming tendrils causing inflammation due to rupture and the release of debris, highlighting limitations of punch biopsies for analysis.

This study identified a new lignan and 21 known compounds from Asiasarum heterotropoides roots, with two compounds showing potential anticancer activity by influencing NO production, FOXP3 expression, and HIF-1α activity in vitro.

In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.

This case study highlights the significance of early diagnosis and treatment of Cushing's syndrome during pregnancy, as it is associated with severe maternal and fetal complications, including stillbirth.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

In this study, researchers established three specific cell lines from Cashmere goat hair follicles and found that cytokeratin 13 might be a novel biomarker for identifying dermal sheath cells.

The researchers in this experimental study developed a thermodynamic model using the Peng-Robinson equation of state to optimize gas antisolvent system conditions for controlling finasteride particle size, aiming to reduce experimental trials and precisely identify precipitation pressures across different temperatures.

This study suggests that immunohistochemistry of keratin and involucrin expression can aid in distinguishing malignant trichilemmoma from other tumors previously diagnosed as such.

This commentary described developing a framework to evaluate how pharmacists in community pharmacy care clinics impact emergency department visits, focusing on conditions they can manage, adverse medication events, and necessary referrals.

Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

This study found that inhibiting the HEDGEHOG-GLI1 pathway could reduce keloid size and gene expression, suggesting it as a potential therapeutic target for keloid pathogenesis.

This study found that 9.29% of rabbits at a Kuala Lumpur farm were infected with scabies, with the majority exhibiting mild crusting severity.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This study found that ursolic acid at 50 mg/kg improved biochemical, hormonal, and ovarian histopathological markers in a rat model of PCOS, suggesting its potential as a therapeutic option.

This study found that rhamnose can restore hair-inducing gene expression in dermal papilla cells and accelerate hair follicle regeneration by promoting the hair cycle into the anagen phase, suggesting its potential therapeutic application for alopecia treatment.

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

This study demonstrated that cortisol, estradiol, and testosterone are preserved in archaeological human hair, allowing for the analysis of ancient stress and reproductive hormone patterns.

This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.

This study found that 5-alpha-reductase inhibitor monotherapy for symptomatic benign prostatic hyperplasia showed some clinical benefit over placebo but was linked to a higher incidence of sexual side effects.

This case report describes a young man with bilateral morphea en coup de sabre, which recurred after being quiescent, highlighting its association with previous head trauma and alopecia.

In this study, facial hypertrichosis occurred in 10% of women treated with isotretinoin for acne, but it resolved spontaneously after the treatment ended.

This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.

Sox13 is a new marker for early hair follicle development and differentiation.

In this study, researchers identified five unique sequences of the ovine KAP13-3 gene, with potential implications for wool traits due to observed amino acid changes.

IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.

This study identified three genes in the ovine KAP13 family on chromosome 1 and found that a specific allele of KRTAP13-2 is associated with improved wool fibre diameter uniformity in Chinese Tan sheep, suggesting its potential use as a marker for enhancing wool traits.

This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.