Pregnancy During the Course of Cushing’s Syndrome: A Case Report and Literature Review

    April 2020 in “ Endocrinology, diabetes & metabolism case reports ”
    Sofía Pilar Ildefonso-Najarro, Esteban Alberto Plasencia Dueñas, Cesar Joel Benites-Moya, Jose Carrion-Rojas, Marcio José Concepción‐Zavaleta
    Image of study
    TLDR Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.
    In a case report from 2020, a 24-year-old pregnant woman with Cushing's syndrome was presented. She had symptoms including weight gain, hirsutism, and hair loss, and was found to have hypokalemia, high nocturnal cortisolemia, and a right adrenal mass. An MRI confirmed an adrenal adenoma, leading to a successful right laparoscopic adrenalectomy. Post-surgery, her blood pressure and blood sugar levels were managed, and she was put on low-dose prednisone. Despite improvements in her Cushing's syndrome, the pregnancy resulted in a stillbirth at 28 weeks. The case highlighted the rarity of pregnancy during Cushing's syndrome due to anovulatory infertility caused by hypercortisolism, the difficulty in diagnosing the syndrome during pregnancy, and the severe risks it poses to both mother and fetus, emphasizing the need for early diagnosis and treatment.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 137 results

      community 1.5 years on fin/min progress pics, thoughts would be great!

      in Progress Pictures  69 upvotes 3 years ago
      A 42-year-old male shared his 1.5-year hair regrowth progress using 1.25mg finasteride daily and regular doses of minoxidil twice a day, and recently started using the Derminator 2. He also mentioned his battle with cancer and Cushing's syndrome, which affected his weight and hair.

      community Damn...I've made some real progress, yeah??

      in Progress Pictures  992 upvotes 3 weeks ago
      A user shared their significant hair regrowth progress using topical minoxidil, oral finasteride, and minoxidil chews, while transitioning to generic versions. They also mentioned using batana oil and microneedling, with no side effects reported.

      community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

      in Female  42 upvotes 3 years ago
      User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

      community Breezula will hit the market in 2026, Cosmo Pharmaceuticals statement!

      in Product  52 upvotes 9 months ago
      Breezula, a hair loss treatment, is expected to cost around $100 a month and is anticipated to be released in 2026. The effectiveness of Breezula is debated, with some suggesting it loses effectiveness over time and others arguing it maintains hair compared to baseline.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

    Similar Research

    5 / 1000+ results
      Complications of Cushing's Syndrome: State of the Art

      research Complications of Cushing's Syndrome: State of the Art

      374 citations, May 2016 in “˜The œLancet. Diabetes & endocrinology”
      Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
      Hyperadrenocorticism in Ferrets

      research Hyperadrenocorticism in Ferrets

      6 citations, January 2013
      Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
      Hirsutism: Diagnosis and Treatment

      research Hirsutism: Diagnosis and Treatment

      26 citations, March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia”
      The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
      The Clinical Evaluation of Hirsutism

      research The Clinical Evaluation of Hirsutism

      67 citations, September 2008 in “Dermatologic therapy”
      Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
      Toward a Diagnostic Score in Cushing's Syndrome

      research Toward a Diagnostic Score in Cushing's Syndrome

      42 citations, November 2019 in “Frontiers in Endocrinology”
      The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.