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      Wound Healing: A Cellular Perspective

      research Wound Healing: A Cellular Perspective

      1160 citations , November 2018 in “Physiological Reviews”
      This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
      Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin

      research Epidermal homeostasis: a balancing act of stem cells in the skin

      1039 citations , February 2009 in “Nature Reviews Molecular Cell Biology”
      This review discusses the reuse of molecular mechanisms involved in embryonic skin development for maintaining adult epidermal homeostasis and reports no new results.
      Vitiligo: A Comprehensive Overview

      research Vitiligo: A comprehensive overview

      532 citations , August 2011 in “Journal of the American Academy of Dermatology”
      This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
      Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

      research Melatonin membrane receptors in peripheral tissues: Distribution and functions

      506 citations , January 2012 in “Molecular and Cellular Endocrinology”
      This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
      Modulating the Stem Cell Niche for Tissue Regeneration

      research Modulating the stem cell niche for tissue regeneration

      480 citations , August 2014 in “Nature Biotechnology”
      This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.
      Cutaneous Wound Healing: Recruiting Developmental Pathways for Regeneration

      research Cutaneous wound healing: recruiting developmental pathways for regeneration

      471 citations , October 2012 in “Cellular and Molecular Life Sciences”
      This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.
      Colon Cancer Stem Cells: Promise of Targeted Therapy

      research Colon Cancer Stem Cells: Promise of Targeted Therapy

      411 citations , April 2010 in “Gastroenterology”
      This review explores various theories of colorectal cancer stem cell biology and highlights the need for better identification and targeting of these cells to advance treatment strategies, but reports no new clinical findings.
      Wound Healing and Skin Regeneration

      research Wound Healing and Skin Regeneration

      359 citations , January 2015 in “Cold Spring Harbor Perspectives in Medicine”
      This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
      Stem Cells and the Niche: A Dynamic Duo

      research Stem Cells and the Niche: A Dynamic Duo

      333 citations , February 2010 in “Cell Stem Cell”
      This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.
      Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

      research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

      326 citations , February 2009 in “˜The œAmerican journal of pathology”
      This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.
      Sexual Hormones in Human Skin

      research Sexual Hormones in Human Skin

      305 citations , February 2007 in “Hormone and metabolic research”
      This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
      Fibroblast Heterogeneity: Implications for Human Disease

      research Fibroblast heterogeneity: implications for human disease

      299 citations , January 2018 in “Journal of Clinical Investigation”
      This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.
      Mucocutaneous Reactions to Chemotherapy

      research Mucocutaneous reactions to chemotherapy

      275 citations , March 1999 in “Journal of The American Academy of Dermatology”
      This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.
      Severe Cutaneous Adverse Reactions to Drugs

      research Severe cutaneous adverse reactions to drugs

      273 citations , May 2017 in “The Lancet”
      This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      The Rotterdam Study: 2012 Objectives and Design Update

      research The Rotterdam Study: 2012 objectives and design update

      247 citations , August 2011 in “European Journal of Epidemiology”
      This article outlines the rationale, design, major findings, and updated objectives of the ongoing Rotterdam Study, without presenting new research data.
      Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

      research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

      232 citations , October 2015 in “International journal of molecular sciences”
      This review discusses the role of epidermal and other adult stem cells in skin repair, focusing on their potential therapeutic applications for non-healing wounds and other skin disorders, but reports no new research results.
      Tracing the Cellular Origin of Cancer

      research Tracing the cellular origin of cancer

      232 citations , January 2013 in “Nature Cell Biology”
      Understanding where cancer cells come from helps create better prevention and treatment methods.
      Signaling Involved in Hair Follicle Morphogenesis and Development

      research Signaling Involved in Hair Follicle Morphogenesis and Development

      223 citations , January 2014 in “International Journal of Molecular Sciences”
      This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
      The Rotterdam Study: 2010 Objectives and Design Update

      research The Rotterdam Study: 2010 objectives and design update

      219 citations , September 2009 in “European journal of epidemiology”
      This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.