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This study found that two injections of platelet-rich plasma were safe but no more effective than placebo in treating mild to moderate erectile dysfunction.

This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.

Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.

Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.

This study reports that simultaneous cystoscopy, electroejaculation, transurethral resection of ejaculatory ducts, and seminal vesiculography were safe and effective in diagnosing and treating concurrent hematospermia and anorgasmia.

This study evaluated the effect of intralesional injections of lyophilized Platelet Derived Growth Factors in 42 patients with Peyronie's disease and found significant reductions in penile curvature and plaque size, along with improvements in Peyronie's Disease Questionnaire scores, suggesting a potential treatment role.

This review discusses the role of norepinephrine release and protein kinase C activation in the development of benign prostatic hypertrophy, suggesting potential targets for new therapies, but it reports no new clinical results.

This study found that supraphysiological doses of testosterone alter endothelial relaxation pathways in hypertensive rats, with varied contributions from nitric oxide, prostanoids, and endothelium-derived hyperpolarizing factors, influenced by estrogen and dihydrotestosterone levels.

This review concludes that preoperative hormonal stimulation with testosterone or DHT may help increase penile length and glans circumference, easing hypospadias surgery and potentially reducing postoperative complications.

This study found that finasteride administration for more than one month before TURP surgery significantly reduces blood loss in patients with benign prostatic hyperplasia.

This study identified several patient-specific factors that can predict both the likelihood of undergoing and failing a post-TURP void trial, aiding in the selection of candidates for immediate assessment.

This study used micro-CT to visualize preputial vessel distribution in a congenital hypospadias rat model, revealing that vessels at the preputial junction with good circulation were well-suited for vascular pedicle flaps in surgery.

This review evaluates existing preclinical and clinical studies on stromal vascular fraction for treating male sexual dysfunction, finding limited data and emphasizing the need for more research before conducting clinical trials.

BPH treatment improved with personalized medicine, new drugs, and less invasive surgeries.

This retrospective study observed no significant difference in the prevalence of incidental prostate cancer between suprapubic prostatectomy and transurethral prostate resection groups, with most tumors being well differentiated and early-stage.

This study found that while new treatments like Optilume, Rezum, and Aquablation have minimal risks of sexual dysfunction, they offer less improvement in lower urinary tract symptoms compared to traditional surgeries like TURP, though Aquablation does reduce ejaculatory dysfunction more effectively than TURP.

This study found that combining 4 mg doxazosin with 0.2 mg tamsulosin improved urinary symptoms with fewer vasodilatory side effects compared to a higher dose of doxazosin in hypertensive males with LUTS.

Low-intensity shock wave therapy is effective in treating erectile dysfunction in diabetic patients.

This study found that terazosin hydrochloride, when used with finasteride, improved prostate volume and lowered blood pressure in BPH patients with high blood pressure, although the overall treatment effect was not significantly different from controls.

This study found that patients with BPH who received finasteride before TURP experienced reduced intraoperative blood loss and improved quality of life one month after surgery compared to those who did not.

This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.

Combination therapy with Finasteride is more effective than alpha-blocker alone for BPH symptoms in small prostate volume.

This study found that low androgen levels in rat penile endothelial cells were associated with a decrease in eNOS-expressing extracellular vesicles and reduced nitric oxide production.

In this case study, a 29-year-old male experienced chronic pelvic pain and erectile dysfunction after finasteride use, with no effective relief from pharmacological and procedural interventions, prompting a shift towards pain education and behavioral strategies due to a possible nociplastic pain mechanism.

In a rat model, this study found that a hydrogel incorporating adipose-derived stem cells and nerve growth factor may aid in the recovery of erectile function following cavernous nerve injury.

In this study, testosterone increased the expression of epithelial sodium channel proteins and mRNAs in rat kidneys, suggesting a potential mechanism for its effect on blood pressure through enhanced sodium reabsorption.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.