Platelet-Rich Plasma for the Treatment of Erectile Dysfunction: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

This study evaluated the safety and efficacy of platelet-rich plasma (PRP) for treating mild to moderate erectile dysfunction (ED) in a randomized, double-blind, placebo-controlled trial with 61 men. Results showed no significant difference between PRP and placebo groups in achieving a minimum clinically important difference in erectile function at 1 month (58.3% for PRP vs. 53.6% for placebo, P = .730). Both groups had similar improvements in erectile function scores at 1 and 6 months, with no significant differences between them. The study concluded that PRP is safe but not more effective than placebo for improving erectile function in men with mild to moderate ED, highlighting the need for standardized protocols and further research.