Effects of Nitrendipine, Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle

    November 1982 in “ Journal of Cardiovascular Pharmacology ”
    Robertson Dr Towart
    Image of study
    TLDR Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
    This study examined the effects of various vasoactive agents on isolated rabbit aortic smooth muscle contractions. Nitrendipine and nifedipine were found to be potent and specific blockers of depolarization-induced contraction in this tissue. Papaverine relaxed both types of contractions equipotently, and minoxidil was effective only in extremely high concentrations. The study confirmed and extended previous results with verapamil and perhexiline.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Warning: Your Rogaine Foam Might Not Contain Minoxidil

      in Minoxidil  373 upvotes 1 year ago
      A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.

      community Minoxidil (5% Rogaine foam) 0.5 Dutasteride

      in Minoxidil  15 upvotes 3 months ago
      A user shared their hair loss experience and treatment routine, which includes using Minoxidil (5% Rogaine foam) and Dutasteride 0.5, along with various supplements and natural oils. They reported positive results and emphasized the importance of liver health and thyroid function, despite skepticism from others about the effectiveness of supplements.

      community 6 months rogaine minoxidil update

      in Progress Pictures  7 upvotes 3 weeks ago
      The user has been using Rogaine (minoxidil), dermastamping, Nizoral shampoo, and spironolactone for 6 months with minimal visible results. They are advised to consider finasteride and be cautious with microneedling frequency and depth.

      community 3 weeks on Minoxidil 5% (rogaine foam)

      in Is this regrowth?  43 upvotes 4 months ago
      The user started using Minoxidil 5% foam and plans to begin finasteride in December, noticing less shedding but uncertain about regrowth after three weeks. Others suggest it takes at least 3-6 months to see significant results, with some recommending adding finasteride and possibly switching to oral Minoxidil.

      community Am I taking out too much foam for a dose? Rogaine Minoxidil

      in Minoxidil 3 years ago
      This conversation discusses the topical application of Minoxidil, with various users providing advice on how to accurately measure a dose and keep it from melting too quickly. Others have shared their experiences using oral finasteride for hair loss treatments.

    Related Research

    1 / 1 results