39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
117 citations,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
20 citations,
November 2017 in “PubMed” A new supplement may treat hair loss by targeting multiple causes like inflammation and stress.
1 citations,
October 2023 in “Biology” Fasting in hens affects thyroid hormones, which regulate feather and hair growth.
October 2024 in “International Journal of Molecular Sciences” Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
January 2024 in “Advanced Science” New microspheres help heal skin wounds and regrow hair without scarring.
FGF9 helps hair follicles grow in small-tailed Han sheep by affecting cell growth and certain signaling pathways.
1 citations,
July 2022 in “British Journal of Dermatology” Targeting specific genes in certain pathways may help treat male pattern baldness.
1 citations,
April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” The mouse models are effective for testing new hair loss treatments.
28 citations,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
29 citations,
January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
January 2025 in “Clinical and Translational Medicine” A specific RNA can help hair growth in baldness by boosting stem cell activity.
13 citations,
March 2021 in “British Journal of Pharmacology” KY19382 helps regrow hair and create new hair follicles.
22 citations,
August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
20 citations,
January 2021 in “Plants” High energy boosts root hair growth in plants, while low energy stops it.
66 citations,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
19 citations,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
176 citations,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
4 citations,
April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
9 citations,
July 2022 in “Journal of Biological Chemistry” WWP2 is crucial for tooth development in mice.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
January 2023 in “Biocell” Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.
4 citations,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
45 citations,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
54 citations,
August 2017 in “Gynecological Endocrinology” Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
7 citations,
January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
December 2021 in “Signal transduction and targeted therapy” Increasing sebum production might help reduce fat and improve metabolism.
12 citations,
January 2020 in “Indian Dermatology Online Journal” Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.