This study highlights the importance of trauma-informed, culturally sensitive, and flexible teaching strategies in public administration education during wartime in Ukraine, emphasizing the integration of digital well-being and burnout prevention to maintain academic continuity and develop resilient, ethically-minded future leaders.
May 2024 in “Journal of molecular structure” This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.
December 2021 in “Daehanhanuihakoeji” This study suggests that combining finasteride with traditional herbal formulas Yongdamsagan-tang or Paljung-san may not interfere with drug metabolism while potentially enhancing anti-inflammatory effects for treating benign prostatic hyperplasia.
September 2014 in “Journal der Deutschen Dermatologischen Gesellschaft” Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
March 2009 in “Dermatology Online Journal” This study reports that blocking the epidermal growth factor receptor in cancer treatments can lead to changes in hair growth and create a "wavy" hair phenotype in some patients.
January 2003 in “Springer eBooks” Certain genes are linked to type 1 and type 2 diabetes in kids, and changes in these genes can also cause other diabetes-related conditions.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
2 citations
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November 2014 in “Pharmaceutical Patent Analyst” This article provides an update on several international patent cases, including a decision that could change Japan's patent term extension practice, but it reports no new research results.
82 citations
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March 2013 in “PLoS ONE” In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.
158 citations
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May 2003 in “Journal of Investigative Dermatology” This study observed that hair follicle mesenchyme in mice exhibits significant plasticity during the hair cycle, with cell migration and changes in papilla size impacting hair production.
75 citations
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March 2014 in “Journal of Investigative Dermatology” This study found that aging mice experience slower and more fragmented hair cycle waves, but transplanting aged skin to a young host can partially restore hair cycling, implicating extracellular factors.
65 citations
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March 2018 in “Journal of Dermatological Science” This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.
54 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This speculative review discusses hair cycle-dependent fibroblast dynamics and possible impacts on human hair growth, synthesizing current literature without presenting new clinical findings.
51 citations
,
March 2001 in “Clinics in dermatology” This study found that bleach treatments significantly increased hair surface roughness and decreased Young's modulus, indicating marked changes in hair's molecular structure which may affect future hair-care product formulation.
49 citations
,
December 2009 in “Journal of Investigative Dermatology” This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
46 citations
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the vitamin D receptor is essential for the self-renewal, migration, and differentiation of epidermal stem cells during skin wound healing in mice.
39 citations
,
April 1992 in “Development” In this study, researchers detailed how hair follicles regenerate after microsurgical amputation, observing a wound reaction involving dynamic dermal-epidermal interactions and changes in extracellular matrix components.
31 citations
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April 2018 in “Royal Society open science” This study found that mange-infected bare-nosed wombats have increased heat loss, higher metabolic rates, altered behavior, and disrupted fatty acid composition compared to healthy individuals.
31 citations
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April 2016 in “Nature communications” This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.
21 citations
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December 2023 in “Journal of Investigative Dermatology” This study highlights multiple factors contributing to hair graying, such as oxidative damage, melanocyte changes, and genetic influences, and suggests that repigmentation may be temporarily reversible, offering potential targets for future treatments while urging caution when applying mouse model findings to humans.
16 citations
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November 2019 in “Nanomedicine” This study discusses the potential of thermoresponsive nanogels for improving dermal delivery of therapeutics, highlighting their ability to enhance skin penetration and control drug release with minimal damage to the skin's natural barrier.
14 citations
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October 2021 in “Dermatology and Therapy” This study found that photoexposure significantly increased the gene expression of altered elastin, MMP12, and LOX, as well as the protein expression of tropoelastin and fibrillin-1, in skin models.
6 citations
,
May 2020 in “Nutrients” This review discusses the effects of calorie restriction on skin aging, highlighting its potential to benefit skin health by reducing age-related and photo-induced changes, although the impact of certain diets remains unexplored.
5 citations
,
March 2001 in “Journal of biomechanics” This study found that anagen hairs require less force to be extracted than telogen hairs in an in vitro pig skin model, indicating different anchorage mechanisms.
4 citations
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November 2024 in “Materials” In this study, researchers created nanowhiskers from crab shell-derived nanochitin that self-assembled into vibrant structural colors within a film. The material, sensitive to environmental changes, shows potential as a food freshness indicator and a sustainable dye for cosmetics due to chitin's biocompatibility.
4 citations
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January 2023 in “Journal of Clinical Investigation” This study identified a recurrent mutation in the endothelin receptor type A associated with mandibulofacial dysostosis with alopecia, and proposed a mechanism involving increased ligand affinity due to structural changes.
4 citations
,
November 2022 in “Frontiers in Immunology” This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.
3 citations
,
August 2013 in “Tropical Journal of Pharmaceutical Research” This study concluded that the Box-Behnken experimental design effectively optimizes the size of finasteride nano-emulsions by assessing the impact of various experimental factors.
2 citations
,
November 2024 in “International Journal of Pharmaceutics X” In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.
2 citations
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August 2024 in “JID Innovations” This study suggests that keratinocytes derived from hair follicles of patients with atopic dermatitis provide a useful model for investigating AD-related inflammation, as they showed greater expression changes of AD markers when stimulated with type 2 cytokines compared to those from healthy donors.