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A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Wool follicles grew fibres for 8-10 days in a serum-free culture, influenced by calcium, glucose, amino acids, and insulin.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Mild thyroid issues don't affect the metabolism and hormones of women with PCOS.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Increasing sleep by 41 minutes daily for a month showed no significant changes in metabolism or hormone levels in healthy women.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Using a combined treatment of minoxidil and metformin can improve hair loss in women by normalizing hormone and metabolism levels.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

Children with metabolic syndrome often have skin problems like dark patches, skin tags, stretch marks, infections, acne, and psoriasis, which are linked to obesity and insulin resistance.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.

Adding 0.2% taurine to Angora rabbits' diet improves wool production and overall health.

More young women are getting diagnosed with PCOS, which can lead to other health problems, but early treatment can help.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

PCOS often causes skin problems due to hormonal and metabolic imbalances.