Recovery from Alopecia Areata in a Patient with Autoimmune Polyglandular Syndrome Type 3

February 2015 in “ Endocrinology Diabetes and Metabolism Case Reports ”

Shinya Makino, Takeshi Uchihashi, Yasuo Kataoka, M. Fujiwara

alopecia areata autoimmune polyglandular syndrome type 3 hyperglycemia insulin therapy anti-insulinoma-associated antigen 2 antibody Hashimoto's thyroiditis metabolic improvement autoimmune type 1 diabetes APS type 3 insulin anti-IA-2 antibody

TLDR Insulin therapy helped a man with autoimmune issues regrow his hair.

A 41-year-old male with autoimmune polyglandular syndrome type 3 (APS type 3) and hyperglycemia experienced total hair regrowth within 2-3 months after successful diabetes control with insulin therapy. Despite the presence of anti-insulinoma-associated antigen 2 antibody and Hashimoto's thyroiditis, insulin therapy led to metabolic improvement and hair recovery. This case suggested that while insulin-mediated metabolic improvement might contribute to alopecia recovery in autoimmune type 1 diabetes patients, it is not the sole factor. Further studies are needed to clarify the association between APS type 3 and alopecia recovery.

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Research cited in this study

2 / 2 results

research Autoimmune Polyglandular Syndrome Type 2, Alopecia Universalis, and Crohn's Disease

8 citations, June 2012 in “Journal of Crohn s and Colitis”

Managing multiple autoimmune diseases in one patient is extremely challenging.

research An Update on Alopecia Areata

38 citations, July 2009 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics”

Alopecia areata is a common autoimmune disease affecting hair follicles, with unclear causes and a need for better treatments.

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