Women's Health Considerations for Lipid Management

    February 2016 in “ Endocrinology and Metabolism Clinics of North America ”
    Robert A. Wild, Elizabeth A. Weedin, Edward A. Gill
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    TLDR Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.
    The document from 2016 addresses the management of dyslipidemia in women, with a focus on pregnancy, polycystic ovarian syndrome (PCOS), and menopause. It recommends screening for dyslipidemia before or early in pregnancy and managing it with diet, exercise, and glycemic control, noting that lipid levels naturally increase during pregnancy and levels above 250 mg/dL may indicate complications. For women with PCOS, it discusses the risks associated with combined oral contraceptives and the impact of insulin resistance on lipid levels. The document also covers menopausal hormone therapy (HT), advising against its use for cardiovascular purposes due to thrombotic risks and suggesting an individualized approach to treatment. It mentions that transdermal HT may have a lower risk of thromboembolism and stroke, but more evidence is needed. Overall, the document emphasizes the importance of lipid management in women's health and the need for careful consideration of treatment options in relation to reproductive status and cardiovascular risk.
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