research A 2018 Approach to Combating Methotrexate Toxicity: Folic Acid and Beyond
New strategies like vitamin A and dextromethorphan can help reduce methotrexate side effects and improve patient adherence.
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870-900 / 1000+ resultsresearch The Evolutionary Trajectory of Primate Skin Appendage Traits
Humans evolved to have less hair and more sweat glands than chimpanzees and macaques.
research cAMP Response Element-Binding Protein 1 (CREB) Is a β-Catenin-Regulated Transcription Factor in Squamous Cell Carcinoma (SCC) Cells
CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.
research Decoding Frontal Fibrosing Alopecia and Lichen Planopilaris: Macrophages Hold the Key?
Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Effects Of Astragalus Membranaceus Extract On Spontaneous Alopecia In Mice
Astragalus extract may help with hair regrowth.
research Lichen Planus Colocalized with Vitiligo: Coincidence?
Some people with the skin color loss condition, vitiligo, also develop the skin inflammation condition, lichen planus, possibly due to local trauma, sun damage, or genetic factors.
research Strivilasa: An Ayurvedic Manuscript on Cosmetic Procedures, Aphrodisiacs, Diseases, and Medicines for Women
The manuscript "Strīvilāsa" offers ancient Ayurvedic knowledge on women's health, beauty treatments, and reproductive care.
research Abstract 2474: The Mechanistic Role of Polyamines in DNA Double-Strand Break Repair
Polyamines help repair DNA breaks and may influence cancer development.
research PLAU and SerpinB2 Role in Apoptosis in Leprosy
PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.
research Importance of Hair in Diagnosis, Management, and Monitoring of Dependent Subjects
Hair analysis is crucial for diagnosing, managing, and monitoring addiction.
research From Genotoxic Stresses to Skin Damage: Distinct, Novel Mechanisms of Skin and Hair Damage in Chemo/Radiation Therapy
Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
research Early and Late Matrix Progenitors Form the Terminally Differentiated Cell Layers of the Hair Follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Spatiotemporal Antagonism in Mesenchymal-Epithelial Signaling in Sweat Versus Hair Fate Decision
Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.
research Deep Phenotyping of Patients with Xeroderma Pigmentosum and Trichothiodystrophy
Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.
research Dermal Wnt/β-Catenin Signaling Controls Hair Follicle Dermal Condensate Size During Development
Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
research Endoplasmic Reticulum Stress Upregulates NKG2D Ligands in the Hair Follicle
Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
research Congenital Generalized Hypertrichosis With a Copy Number Variation on Chromosome 17q24
A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.
research Bald’s Leechbook and the Construction of Male Health in Anglo-Saxon England
The Leechbook shows how hair and sexual health were key to medieval masculinity and some remedies may still be useful.
research Deletion of the MAD2L1 Spindle Assembly Checkpoint Gene Is Tolerated in Mouse Models of Acute T-Cell Lymphoma and Hepatocellular Carcinoma
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
research Alopecia Universalis Hair Regrowth with Hormones
A man with severe hair loss regrew hair after hormone treatment.
research Comment On: Serum Vitamin D3 Levels And Diffuse Hair Fall Among The Student Population In South India: A Case-Control Study
Vitamin D supplements might help reduce hair fall.
research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Seborrhea-Like Dermatitis Phenotype in the Mpzl3 Knockout Mice
MPZL3 is crucial for seborrheic dermatitis development.
research The Study of Consistent Properties of Gelatinous Shampoo with Minoxidil
The shampoo with minoxidil maintains its consistency well and spreads evenly on the scalp.
research Dermabrasion and Microdermabrasion: Rationale, Application, Safety Concerns, and Complications
Understanding and careful application of dermabrasion and microdermabrasion can minimize risks and improve patient outcomes.
research An Analysis of Ultrastructure of the Hair of Children Treated With Valproic Acid
Valproic acid may cause temporary hair changes like loss or thinning in children.
research PLOS Science Wednesday: Hi Reddit, I'm Zhengquan Yu, Here to Talk About My Recent PLOS Genetics Paper That Has Identified the Key Role of a MicroRNA in Hair Loss. I'm Joined by Maksim Plikus, Who Studies
MicroRNA miR-22 causes hair loss by making hair follicles regress early.
research Expression Patterns of TRα and CRABPII Genes in Chinese Cashmere Goat Skin During Prenatal Development
TRα and CRABPII genes change their activity levels during goat fetal skin development.
research Induction of Cellular Senescence and Hair Follicle Stem Cell Dysfunction Upon p14ARF and p16Ink4a Expression in the Skin
p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.