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    Glossary Infundibular Region

    upper part of a hair follicle below skin's surface

    The infundibular region refers to the upper part of a hair follicle, just below the opening of the follicle at the skin's surface. This area is crucial for the passage of sebum and other substances from the sebaceous glands to the skin, and it plays a significant role in conditions like acne and folliculitis.

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    1. Pulling force deforms hair follicle root sheath nuclei and surrounding dermal collagen matrix differently at infundibulum, isthmus and suprabulbar regions Experimental Dermatology · 2019 · 2 citations
    2. Seborrheic karatosis, a tumor of the infundibular and isthmus of hair follicles: Identification of hair sheath keratins and histopathological features suggesting hair follicle origin. The Nishinihon Journal of Dermatology · 1989 · 2 citations
    3. Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp British Journal of Dermatology · 1999 · 100 citations
    4. Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia British Journal of Dermatology · 2009 · 54 citations
    5. Tight junctions form a barrier in porcine hair follicles European journal of cell biology · 2015 · 21 citations
    6. D2-40 Expression in Primary Scarring and Nonscarring Alopecia The American Journal of Dermatopathology · 2010 · 3 citations
    7. 1388 Clinicopathological characteristics of fibrosing alopecia in a pattern distribution: A single-center, retrospective study Journal of Investigative Dermatology · 2023
    8. Hair follicles, their disorders and their opportunities Drug Discovery Today: Disease Mechanisms · 2008 · 48 citations
    9. Morphometric Analysis of the Human Scalp Hair Follicle: Practical Implications for the Hair Transplant Surgeon and Hair Regeneration Studies Dermatologic Surgery · 2010 · 51 citations
    10. Spatial transcriptome reveals disturbance of peri-infundibular immune infiltration in androgenetic alopecia Research Square (Research Square) · 2023
    11. Recurrent inverse necrotizing infundibular crystalline folliculitis Journal of Cutaneous Pathology · 2024 · 1 citations
    12. Androgen receptor expression in male pattern baldness patients Chinese Journal of Aesthetic Medicine · 2012
    13. Single-cell analysis of 2,3,7,8-tetrachlorodibenzo- <i>p</i> -dioxin (TCDD)-treated murine skin demonstrates that sebaceous gland differentiation precedes <i>Ahr</i> -dependent seboatrophy with elevated expression of infundibular <i>Blimp1</i> bioRxiv (Cold Spring Harbor Laboratory) · 2026
    14. Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics International Journal of Molecular Sciences · 2024
    15. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004 · 405 citations
    16. The role of the microbiome in scalp hair follicle biology and disease Experimental Dermatology · 2019 · 73 citations
    17. Methotrexate Reactions Weekly · 2011
    18. Deciphering the functions of the hair follicle infundibulum in skin physiology and disease Cell and Tissue Research · 2014 · 38 citations
    19. Áreas de alopecia en región frontal Revista del Centro Dermatológico Pascua · 2025
    20. Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles Differentiation · 1994 · 130 citations
    21. Early stage alopecia areata is associated with inflammation in the upper dermis and damage to the hair follicle infundibulum Australasian Journal of Dermatology · 2013 · 22 citations
    22. Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin PLoS ONE · 2014 · 62 citations
    23. Assessment of markers expressed in human hair follicles according to different skin regions Advances in Clinical and Experimental Medicine · 2018 · 6 citations
    24. Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells Cancer Research · 2010
    25. 1351 Investigation of the molecular identity of the junctional zone in human 2018
    26. Lymphocytic mediated alopecia: histological classification by pattern analysis Clinics in Dermatology · 2001 · 29 citations
    27. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005 · 205 citations
    28. The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15 Journal of Cutaneous Pathology · 2014 · 28 citations
    29. Comparing the delivery to the hair bulb of two fluorescent molecules of distinct hydrophilicities by different nanoparticles and a serum formulation International Journal of Pharmaceutics · 2021 · 2 citations
    30. Immunohistochemistry of Canine Hair Follicle Stem Cells (cHFSCs) by using CK15 and CK19 Journal of animal research · 2020