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    GlossaryHair Follicle Infundibulum

    upper part of the hair follicle extending to sebaceous gland

    The hair follicle infundibulum is the upper part of the hair follicle, extending from the opening of the follicle at the skin's surface down to the point where the sebaceous (oil) gland attaches. This region is crucial for the passage of sebum and other substances to the skin's surface, and it plays a role in conditions like acne and folliculitis.

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      an estrogen promoting hair regrowth more commonly used in women

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Is Finasteride the only way to reduce scalp DHT?

      in Chat  27 upvotes 6 days ago
      A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 2 weeks ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 2 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 1 year ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.