37 citations
,
August 2024 in “Current Issues in Molecular Biology” This review summarizes recent findings on keratins 6, 16, and 17, highlighting their role in keratinocyte behavior and nuclear functions, and discusses their potential as biomarkers for various skin pathologies, including damage, inflammation, and cancer, rather than in healthy skin.
34 citations
,
November 2010 in “Development” In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.
32 citations
,
November 2011 in “International Journal of Dermatology” This article reviews central centrifugal cicatricial alopecia, focusing on its multifactorial etiology and challenges in clinical diagnosis, and calls for more research and better treatment options.
30 citations
,
April 2007 in “Dermatologic Clinics” This review discusses the mechanisms by which isotretinoin and hormonal therapy treat acne through their effects on sebaceous glands, reporting no new clinical results.
27 citations
,
August 2003 in “Anais Brasileiros de Dermatologia” This review discusses the roles of several neuropeptides in skin-immune interactions and inflammatory responses, reporting no new results and emphasizing the need for further study in conditions such as psoriasis and dermatitis.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.
21 citations
,
August 2014 in “Journal of Cell Communication and Signaling” This study found that Tsukushi facilitates wound healing in mice by regulating macrophage function and myofibroblast differentiation.
17 citations
,
January 2016 in “Dermatology research and practice” In this study, topical Emu oil delayed burn wound healing but increased hair follicle activity and collagen synthesis in Balb/c mice.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
12 citations
,
June 2023 in “International Journal of Molecular Sciences” This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
9 citations
,
January 2018 in “Medical research archives” This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.
7 citations
,
October 2024 in “Cells” This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
7 citations
,
January 2019 in “Journal of clinical medicine research” This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.
6 citations
,
July 2024 in “Cureus” This review explores the applications of magnetized water in agriculture and medicine and notes potential benefits for human health, but it presents no new experimental findings.
6 citations
,
December 2023 in “Journal of Clinical Medicine” This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.
4 citations
,
April 2021 in “Frontiers in Immunology” This study found that clusters of mRNAs and lncRNAs in the peripheral blood of PCOS patients were aberrantly expressed, and certain lncRNA-mRNA pairs in the chemokine signaling pathway may be genetically related to PCOS.
3 citations
,
May 2025 in “Journal of Ovarian Research” This review discusses the recent progress in understanding the role of m6A modifications in the development of polycystic ovary syndrome and reports no new clinical findings.
1 citations
,
October 2012 in “Medical Hypotheses” The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.
This review synthesizes current advances in transcriptomics and RNA regulatory networks, alongside stem cell-derived skin organoid research, to propose a conceptual framework for understanding and potentially guiding regenerative skin repair, without claiming clinical readiness.
In this study, researchers developed a novel bio-patch from decellularized freeze-dried tumor tissues and hair melanin nanoparticles, which demonstrated enhanced wound healing in vivo by reducing oxidative stress, suppressing inflammation, and promoting angiogenesis.
January 2024 in “Wiadomości Lekarskie” In this study, wounds treated with a combination of 0.02% Decamethoxine and Blastomunil showed enhanced healing and epithelization by the 14th day, leveraging the immunomodulatory and antimicrobial properties of the agents.
May 2023 in “Antioxidants” In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.
February 2023 in “JAAD Case Reports” Scalp tattooing may trigger hair regrowth in alopecia universalis.
January 2008 in “US endocrinology” This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.
This review discusses comprehensive information on hair growth, its clinical and environmental influences, and provides a detailed guide for diagnosing hair loss, but reports no new clinical results.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
48 citations
,
May 2018 in “Expert Opinion on Therapeutic Targets” This review discusses how modern lifestyle factors affecting gut health may contribute to Alopecia Areata in genetically predisposed individuals, reporting no new results but suggesting the need for long-term interventions.
47 citations
,
March 2017 in “Materials Science and Engineering: C” In this study, decellularized human amniotic membrane was found to promote wound healing and reduce scar formation in rats with full-thickness skin defects, compared to traditional clinical treatments.
January 2026 in “International Journal of Cosmetic Science” This study observed that eco-friendly PALF forms a protective physical barrier on the skin, helping limit the impact of environmental pollutants and offering additional benefits for skin and hair in various cosmetic formulations.