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    Glossary Induced Pluripotent Stem Cells

    cells reprogrammed from adult cells to an embryonic-like state

    Induced Pluripotent Stem Cells (iPSCs) are a type of stem cell that scientists create by reprogramming adult cells, such as skin or blood cells, to revert to an embryonic-like state. This process allows these cells to potentially develop into any type of cell in the body, making them valuable for research, regenerative medicine, and disease modeling.

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    1. Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments International Journal of Medical Sciences · 2020 · 9 citations
    2. Engineering Hair Follicle Regeneration: Harnessing Stem Cell Technologies, 3D Bioprinting, and Epigenetic Modulation for Precision Therapeutics 2025
    3. Advancements and challenges in stem cell transplantation for regenerative medicine Heliyon · 2024 · 55 citations
    4. Use of Induced Pluripotent Stem Cells in Dermatological Research 2014 · 15 citations
    5. Hairy tale of signaling in hair follicle development and cycling Seminars in cell & developmental biology · 2012 · 161 citations
    6. Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies Current Pharmaceutical Biotechnology · 2011 · 9 citations
    7. Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia Frontiers in Bioengineering and Biotechnology · 2020 · 119 citations
    8. Human hair regeneration using organoids and hair-on-chip technologies Lab on a Chip · 2026
    9. Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023 Journal of Biochemistry and Molecular Biology · 2022 · 2 citations
    10. Skin tissue engineering Stembook · 2009 · 12 citations
    11. Next generation human skin constructs as advanced tools for drug development Experimental Biology and Medicine · 2017 · 69 citations
    12. 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing Journal of Investigative Dermatology · 2024
    13. Microfluidic Technology for the Generation of Cell Spheroids and Their Applications Micromachines · 2017 · 125 citations
    14. Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders Journal of Stem Cell Research & Therapeutics · 2017 · 1 citations
    15. Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids Organoid · 2022 · 2 citations
    16. An induced pluripotent stem cell-based approach for hair follicle development and regeneration Regenerative Therapy · 2024
    17. Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis Neural Regeneration Research · 2024 · 10 citations
    18. Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix Stem Cell Research & Therapy · 2022 · 3 citations
    19. Application and progress of induced pluripotent stem in chronic wound healing: a narrative review BMC Plastic and Reconstructive Surgery · 2026
    20. MicroRNA profiles of four induced pluripotent stem cell lines derived from distinct tissues BMC Research Notes · 2025
    21. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    22. Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury American Journal Of Pathology · 2026
    23. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    24. Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach Journal of Tissue Engineering · 2024
    25. Advances in Microengineered Platforms for Skin Research JID Innovations · 2024 · 12 citations
    26. Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells International Journal of Molecular Sciences · 2025 · 3 citations
    27. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    28. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    29. Causes and therapeutic limitations of clinical alopecia and the advent of human pluripotent stem cell follicular transplantation Stem Cell Research & Therapy · 2025 · 1 citations
    30. Modulating the stem cell niche for tissue regeneration Nature Biotechnology · 2014 · 480 citations