TLDR Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
The document from 2013 discusses the potential of human hair follicles in medical research, emphasizing their complex nature and the noninvasive advantages they offer. It highlights the growing interest in using stem cells from hair follicle cells in regenerative medicine and the current applications of plucked hair follicles in diagnostics and clinical settings. These applications include their use as autologous epidermal equivalents, as well as in pharmacokinetic and pharmacodynamic studies. The document suggests that hair follicle shafts could serve as a surrogate molecular model for internal organs, offering a noninvasive diagnostic tool for a range of human diseases, which may become a practical approach in the future.
Cited in this study
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8 citations
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April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
550 citations
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December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
17 citations
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October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
48 citations
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August 2001 in “Experimental dermatology” Researchers created a quick, cost-effective way to make skin-like tissue from hair follicles and fibroblasts.
1010 citations
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August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
745 citations
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February 1992 in “Trends in genetics” Hair follicles create different cell layers and proteins, controlled by various molecules.