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research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing

188 citations , October 2012 in “The AAPS Journal”

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

research Plucked Human Hair as a Tissue to Assess Pharmacodynamic Endpoints During Drug Development Studies

23 citations , May 2005 in “British Journal of Cancer”

Plucked human hair can be used to study drug effects on certain cell markers.

research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and Across the Skin

1 citations , February 2024 in “Pharmaceutics”

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

research Acute and 30-Day Oral Toxicity Studies of a Novel Coccidiostat – Ethanamizuril

13 citations , July 2019 in “Toxicology research”

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

research Gas-Propelled Anti-Hair Follicle Aging Microneedle Patch for the Treatment of Androgenetic Alopecia

January 2025 in “Journal of Controlled Release”

A new microneedle patch helps treat hair loss by improving drug delivery to hair follicles.

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community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 9 months ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

community The story of RU58841/ PSK3841

Typical-Promise-3001 in Research 622 upvotes 1 year ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 84 upvotes 1 year ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 1 year ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 2 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

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