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Glossary Plucked Hair Follicles

hair strands manually removed with root and surrounding tissue

Plucked hair follicles refer to hair strands that have been manually removed from the scalp or body, including the root and surrounding tissue. This process is often used in scientific research to study hair growth, hair loss conditions like alopecia, and for hair transplantation procedures.

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Research

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Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

research Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia

20 citations , April 2014 in “Dermatologic Therapy”

This study reported that sulfotransferase activity in plucked hair follicles can predict treatment response to 5% topical minoxidil in women with androgenetic alopecia with high sensitivity and specificity.

research Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature

17 citations , July 2019 in “Lupus Science & Medicine”

In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.

research Novel Application of Layered Expression Scanning for Proteomic Profiling of Plucked Hair Follicles

7 citations , January 2005 in “Dermatology”

This study demonstrates that LES-hair can detect differential protein expression in specific regions of plucked hair follicles, suggesting its potential for research and clinical applications like monitoring treatment effects in alopecia and cancer therapies.

Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil Treatment in Brazilian Female Pattern Hair Loss Patients

research Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients

4 citations , December 2019 in “Dermatologic Therapy”

Hair enzyme activity predicts minoxidil success in Brazilian women with hair loss.

research LB788 Development of a novel three-dimensional human epidermal model from plucked hair follicle-derived keratinocytes

July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.

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Community Join

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community How true is the statement: dead follicles don't grow back?

112 upvotes 1 year ago

Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 5 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community My story: Trying to halt diffuse hair loss for past couple of years but got acute hair fall after quitting minoxidil and finasteride on my dermatologist recommendation

9 upvotes 1 year ago

A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.

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Learn

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learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

Can eyebrows be transplanted in a hair transplant procedure? Eyebrow transplants are possible using hair transplant techniques for fuller eyebrows.
Where do they take hair from for a hair transplant? Transplant hair is usually taken from the back and sides of the scalp, where hair resists pattern loss; clinics say body hair can be used when scalp donor supply is short.
Can hair be taken from other parts of the body for hair transplantation? Body hair can be used for transplantation but is generally a secondary option.
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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Verteporfin

chemical that might completely regrow follicles from hair transplant extractions

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Trichogen® (foligain)

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

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Clinics

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Experts

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Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas