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Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Minoxidil helps hair growth by activating enzymes in hair follicles.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Certain drugs that block specific enzymes can help treat prostate diseases.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

Finasteride may protect brain and improve behavior in rats with liver failure.

Higher iron levels in the blood are not linked to increased hair loss in women.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

The infant with a urea cycle disorder improved with treatment and a liver transplant.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

HSL treatment speeds up hair growth and reduces oxidative stress in hair follicles of ob/ob mice.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.