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Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

This study found that ectodermal precursor cells derived from human induced pluripotent stem cells may enhance hair follicle morphogenesis through improved epithelial-mesenchymal interactions when cocultured with dermal cells.

In this study, trichocytes were shown to have potential for alternative differentiation, with mesenchymal cell influences playing a critical role in determining this process.

This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.

This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.

This study found that combining TIMP-1 with graphene oxide promoted skin tissue regeneration in rats and provided sustained release of TIMP-1 over 40 days.

This study found that CD200-negative human hair follicle bulge cells have a higher hair-regenerative capability compared to CD200-positive cells, suggesting that reduced CD200 expression may enhance hair regeneration, providing insights for improving bulge cell-based hair restoration techniques.

This study demonstrated that novel cryomicroneedles loaded with hair follicle organoids (cryoMN@HFOs) can effectively deliver and develop into functional hair follicles after intradermal transplantation in animal experiments, suggesting promising potential for human hair follicle reconstruction.

In this study, researchers found that the synthetic stress hormone dexamethasone caused opposite effects on hair growth-related proteins, reducing SFRP2 and increasing SFRP3, which respectively stimulate and inhibit hair follicle cell proliferation in human dermal papilla cells.

This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.

This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.

VIP reduces hair pigmentation by decreasing melanin production.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This study found that adding epidermal growth factor to mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats compared to stem cells alone.

This review discusses strategies for identifying and characterizing adult stem cells in mice and highlights their potential and limitations, but reports no new experimental results.

This study found that using three-dimensional cell culture with Matrigel enhances the biological function and stemness of stem cells, leading to improved soft tissue repair and healing by activating the host microenvironment and autologous stem cells.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.

In this study, KY19382 was observed to promote hair regeneration and de novo hair follicle formation in mice by activating Wnt/β-catenin signaling, suggesting its potential as a therapeutic for alopecia.

This study successfully used noninvasive bioluminescence imaging to monitor hair generation in vivo after transplanting hair follicle stem cells in mice.

This study found that selecting human hair follicles at a defined anagen stage based on their in vivo growth rate leads to more consistent results in organ culture, with minoxidil significantly enhancing hair growth in these follicles.

This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.

This study found that a newly developed hemi-vascularized sandwich method significantly improved the regeneration and maturity of hair follicles compared to other transplantation approaches in rat models.

This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.

In this study, researchers developed a new 3D skin equivalent assay using mouse epidermal and dermal cells that successfully regenerated organized hair follicles, outperforming a 2D model in hair follicle orientation and quantity, and enhanced hair growth when Wnt3a was added.

In this study, researchers developed a relatively simple punch assay for regenerating hair follicles using mouse or human cells, finding efficient hair formation with mouse cells but low efficiency with human cells on reconstituted human skin.

This review discusses the advantages of robotic hair transplantation using the ARTAS iX robot compared to manual Follicular Unit Extraction, emphasizing enhanced precision, speed, and hair preservation capabilities, and reports no clinical results.