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Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

This study found that after injury, the bone marrow microenvironment's increased Wnt10b expression supports hematopoietic stem cell regeneration by enhancing Wnt signaling, revealing a vital interaction during recovery.

This review describes recent advances in the study of epidermal stem cells and their importance in regenerative medicine and skin tissue engineering, but provides no new clinical results.

This study suggested that non-colony dissociated hiPSCs can be effectively differentiated into functional RPE cells, and hiPSC-RPE cell spheroids showed promise for use in subretinal transplantation in animal models of retinal degeneration.

This study suggests that using sebaceous glands from rat tail skin samples may effectively capture hair follicle stem cells, potentially aiding skin regenerative medicine when available tissue is limited.

The researchers described a chip-based bioreactor platform for dynamic perfusion, which may enhance in vitro skin models by introducing mechanical shear stress and extending culture periods.

In this study, only a subset of proposed biomarkers universally responded to priming in mesenchymal stromal cells, suggesting limited utility for standardized potency assays across different MSC types and conditions.

This study introduced a new in vivo angiogenesis assay using Gelfoam implanted in ND-GFP transgenic mice to efficiently identify angiogenesis stimulators and inhibitors through GFP visualization.

In this study, bioengineered hair germ microspheres made from HME hydrogels promoted hair follicle regeneration in vivo, suggesting a promising approach for hair loss treatment.

Minoxidil solution and foam both increase hair growth, but the solution works better than the foam.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This study found that bioluminescence imaging can feasibly and non-invasively monitor hair follicle regeneration in mouse models by tracking transplanted hair follicle stem cells expressing a luciferase reporter gene.

This article reviews methods to enhance epithelial–mesenchymal interactions for hair follicle bioengineering but does not present new experimental results; it emphasizes optimizing combinations for successful regeneration.

This review discusses the current challenges and strategies in hair follicle bioengineering for treating hair loss and reports no new clinical results; it highlights ongoing hurdles and future directions for developing functional hair regeneration therapies.

This study found that an improved flap model in nude mice significantly reduces the time needed for hair induction compared to the traditional method, likely due to enhanced blood supply at the transplantation sites.

This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.

This study found that transplanting trichogenous dermal cells significantly enhanced the restoration of in vivo-damaged hair follicles in a nude rat model, with a combination of dermal papilla and sheath cells proving more effective than either cell type alone.

In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.

This study found that mature dermal adipocytes have high plasticity, undergoing dedifferentiation and redifferentiation, which plays a significant role in hair cycling and wound healing.

This study reports that transplantation and in vivo reprogramming using specific reprogrammed cell types can generate skin appendage-like structures in adult mice, suggesting potential therapeutic avenues for skin regeneration and disorders.

This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.

This study found that human iPSC-derived melanocytes from vitiligo patients successfully integrated into mouse hair follicles and epidermis, demonstrating potential for personalized therapy for depigmentation.

This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.

This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.

This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

This study found that human induced pluripotent stem cells differentiated precisely to express certain markers during a specific window could enable successful hair follicle generation when transplanted.

This study found that insulin promotes corneal epithelial wound healing and nerve recovery in diabetic mice through Wnt signaling, suggesting its potential as a protective factor for diabetic corneal damage.

In this study, after long-term observation of human scalp hair follicles over 16 years, the researchers found that a topical 5% minoxidil solution could stimulate hair regrowth after a period of dormancy, though with reduced growth rates and hair diameter.

This study demonstrated that human iPSC-derived melanocytes, when transplanted into mice, can reconstitute pigmented hair follicles and integrate into normal tissue, suggesting their potential as a cellular therapy for depigmentation.