12 citations
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July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
27 citations
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November 2005 in “Archives of Dermatological Research” This study found that selecting human hair follicles at a defined anagen stage based on their in vivo growth rate leads to more consistent results in organ culture, with minoxidil significantly enhancing hair growth in these follicles.
13 citations
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October 2010 in “Methods in molecular biology” This article discusses the development and research applications of human hair follicle organ culture techniques, highlighting its potential to explore biological processes beyond dermatology.
June 2025 in “Frontiers in Physiology” This study demonstrated that PGF 2α significantly stimulates hair growth in human hair follicles via a receptor-driven mechanism, with a notably stronger response in intermediate follicles than in terminal ones, suggesting potential clinical significance for conditions like alopecia.
January 2008 in “Bradford Scholars (University of Bradford)” This study supports that an antibody response against anagen-specific hair follicle antigens, including trichohyalin and keratin 16, may play a role in alopecia areata.