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Topical caffeine improves hair loss intensity, speed, and shedding, and works better with minoxidil/azelaic acid.

Minoxidil with caffeine works better for hair loss than minoxidil alone.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

Improving how drugs are absorbed through the skin could better treat mange in wombats.

Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Fullerenes show potential in skin care but need more safety research.

Nonionic liposomes are the best for delivering genes to skin cells.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.

Claudin-1 is important for the barrier function and growth of hair.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

Cosmeceuticals are popular for their skin health benefits and anti-aging effects.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.