Nutrients Regulation of Skin Cells From Canines and Cats Via Wnt/β-Catenin Signaling Pathway

February 2025 in “ Frontiers in Veterinary Science ”

Xue Sun, Yan Ma, Yuan Gao, Jia Liu, Yunliang Li, Lei Lv

Wnt/β-catenin signaling pathway keratin hydrolyzed egg yolk lecithin fish collagen peptide β-catenin nuclear translocation Wnt signaling β-catenin

Studysummary This study found that keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide promoted β-catenin nuclear translocation and increased gene expression related to hair regeneration in canine and cat skin cell lines, suggesting these nutrients may help improve hair regeneration in pets.

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The study highlights the importance of the Wnt/β-catenin signaling pathway in hair regeneration for pets, specifically canines and cats. It identifies keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide as nutrients that promote β-catenin nuclear translocation and enhance the expression of target genes in skin cell lines. These findings suggest that these nutrients could be beneficial in promoting hair regeneration and addressing hair loss in pets, which is crucial for their overall health and appearance.

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