Nutrients Regulation of Skin Cells From Canines and Cats Via Wnt/β-Catenin Signaling Pathway

    February 2025 in “ Frontiers in Veterinary Science ”
    Xue Sun, Yan Ma, Yuan Gao … Lei Lv
    Studysummary This study found that keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide promoted β-catenin nuclear translocation and increased gene expression related to hair regeneration in canine and cat skin cell lines, suggesting these nutrients may help improve hair regeneration in pets.
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    Research cited in this study 11

    1. Dissecting Hair Breakage in Alopecia Areata: The Central Role of Dysregulated Cysteine Homeostasis Amino Acids · 2024
    2. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    3. Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro Skin Pharmacology and Physiology · 2021
    4. KY19382, A Novel Activator of Wnt/β-Catenin Signalling, Promotes Hair Regrowth and Hair Follicle Neogenesis British Journal of Pharmacology · 2021
    5. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    6. Role of the Wnt Signaling Pathway in Keratoacanthoma Cancer reports · 2019
    7. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    8. Bald Thigh Syndrome in Sighthounds: Revisiting the Cause of a Well-Known Disease PloS one · 2019
    9. STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction Journal of Investigative Dermatology · 2016
    10. Coat Condition, Housing Condition, And Measurement Of Fecal Cortisol Metabolites: A Non-Invasive Study About Alopecia In Captive Rhesus Macaques (Macaca Mulatta) Journal of Medical Primatology · 2005
    11. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999