research Correlation of Immunological Variables of Interleukin-17 and Heat Shock Protein-70 in Ethnic Women with Polycystic Ovary Syndrome
A 3-month treatment improved PCOS symptoms and reduced certain immune proteins.
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research Differential Proteomics of Lesional vs. Non-Lesional Biopsies Revealed Non-Immune Mechanisms of Alopecia Areata
Non-immune factors play a significant role in alopecia areata.
research MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression
MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
research Inflammasome Proteins as Biomarkers of Injury and Disease
Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Erythematous Cutaneous Nodules Caused by Adulterated Cocaine
Talc in street cocaine can cause immune-reactive skin nodules where injected.
research Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks
Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
research New-Onset Systemic Lupus Erythematosus Beginning as Class V Lupus Nephritis After COVID-19 Vaccination
COVID-19 vaccination may trigger lupus in some people.
research Antigen Presenting Cells in the Skin of a Patient with Hair Loss and Systemic Lupus Erythematosus
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research Dietary Grape Powder Inhibits Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Eating grape powder may reduce the severity of skin allergy symptoms.
research Physiological and Pharmacological Features of the Non-Saponin Components in Korean Red Ginseng
Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Analysis of Finasteride Treatment and Its Withdrawal in Rat Hypothalamus and Hippocampus at Whole-Transcriptome Level
Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
research Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Inheritance-Specific Dysregulation of Th1 and Th17-Associated Cytokines in Alopecia Areata
Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.
research Endoplasmic Reticulum Stress Upregulates NKG2D Ligands in the Hair Follicle
Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research CYLD Cutaneous Syndrome Tumors Demonstrate Increased NF-kB Signaling and Diminished Collagen Organization
Skin tumors with CYLD cutaneous syndrome show more NF-κB activity and less organized collagen.
research Effect of Conditioned Media Collected from Human Amniotic Fluid-Derived Stem Cells on Skin Regeneration and Photo-Aging
Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.
research Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man
A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.
research Investigation of Hub Genes and Immune Infiltration in Androgenetic Alopecia Using Bioinformatics Analysis
Immune activities and specific genes are important in male pattern baldness.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
research Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending
The research identified key proteins and genes that may influence wool bending in goats.