Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.

This study found that exosomes and secretome derived from rat hair follicle stem cells show promising potential for wound healing and tissue repair, demonstrating significant wound closure and suggesting their broader applicability in regenerative medicine.

This study found that in patients with elevated fibrinogen levels undergoing revision rhinoplasty, PDRN decreased M1 cytokines and increased M2 cytokines, potentially offering a new therapeutic approach, but further research is needed to understand its mechanisms and effects fully.

In this case-control study, researchers found that patients with alopecia areata had significantly higher serum levels of interleukin-18 and NLRP3 compared to healthy controls, suggesting a potential link between these inflammatory markers and the disease.

This review discusses how regulatory T cells, known for their immunosuppressive role, also produce repair mediators critical for tissue repair and regeneration, acting on non-immune cells in tissue-specific contexts, and highlights areas for future research in tissue repair, fibrosis, and cancer.

This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.

A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.

This study found that PX-12 inhibited the NLRP3 inflammasome and reduced psoriasis-like symptoms in a mouse model, suggesting its potential as a treatment for psoriasis.

This study found that interleukin-12 signals play a role in hair follicle immune privilege collapse in ex vivo alopecia areata models, and a TYK2 inhibitor may help prevent or reverse this process.

This review discusses potential biomarkers for alopecia and their significance, and while it highlights areas for future research, it reports no new clinical results.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Higher levels of IL-1a and IL-1RA were found in severe alopecia areata cases.

In this study, researchers found that people with Parkinson's disease showed higher levels of inflammasome proteins, including caspase-1, ASC, and IL-18, compared to healthy individuals, suggesting these proteins as reliable biomarkers for inflammation in PD.

This research found that certain inflammasome proteins, like caspase-1, ASC, IL-18, and IL-1β, were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH) compared to controls and suggested these proteins could serve as reliable biomarkers for inflammation, potentially predicting worse outcomes.

This study reports that SARS-CoV-2 infection, COVID-19 vaccination, and off-label dupilumab treatment may exacerbate psoriasis, with overlapping inflammatory pathways involving cytokines like IL-17 and TNF-α. Histopathological similarities between psoriasis flares and COVID-19 skin manifestations were noted, suggesting a potential connection requiring further research.

This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.

This study identifies NFAT5 as a crucial transcription factor necessary for triggering innate immune responses in the blood vessel lining that lead to atherosclerosis under hypertonic stress conditions.

This review examines the role of autoinflammation and immune dysregulation in hidradenitis suppurativa, linking it to genetic factors and autoinflammatory syndromes, but highlights the need for further research to fully understand its pathogenic mechanisms.

This study found that glycyrrhizic acid may reduce the cutaneous toxicity caused by Osimertinib in mice, suggesting its potential as an adjunct treatment in clinical settings.

This paper discusses potential links between fat distribution, adipocyte dysfunction, and inflammatory markers in PCOS patients, without presenting new clinical data.

This review explores the complex factors involved in alopecia areata, such as immune and genetic influences, and discusses advances in diagnostic and therapeutic approaches, while reporting no new clinical results.

This study found that fermented Flammulina velutipes polysaccharides showed higher antioxidant and anti-inflammatory capacities than non-fermented ones, suggesting potential use in functional foods and health products.

This review suggests that mucosa-associated invariant T cells may regulate the host response to SARS-CoV-2 and could be potential targets for COVID-19 management, but it reports no new clinical results.

This review discusses the role of keratinocytes in hidradenitis suppurativa, highlighting their genetic and metabolic influences on disease progression without presenting new clinical results.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

This study found that homozygous mutant mice with a hypomorphic CD18 mutation developed a chronic inflammatory skin disease resembling human psoriasis, potentially implicating additional genetic factors in disease susceptibility.

This review describes the clinical, trichoscopic, and histopathological features of hair disorders linked to autoimmune diseases and reports no new clinical results.

In this study, researchers reported that IL-17C plays a key pro-inflammatory role in human skin diseases and may be a promising therapeutic target for inflammatory skin conditions.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

This study reviewed changes in marketing practices of Australian clinics after a regulatory ban on direct-to-consumer advertising of stem cell products, finding improvements yet also limitations in addressing misleading claims and consumer safety.