January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
September 2019 in “Rheumatology advances in practice” This case study highlights the difficulties in diagnosing and treating interstitial lung disease, emphasizing the complex nature of ILD management and the need for further research and clearer guidelines.
November 2022 in “Journal of Drug Delivery and Therapeutics” This review discusses the concept and treatment of diffuse hair loss, known as Intithār al-Sha‘r, in the Unani system, drawing from classical Unani literature without reporting new clinical results.
11 citations
,
January 2023 in “World Journal of Clinical Cases” This study suggests that idiopathic hirsutism may involve higher local androgen synthesis despite normal serum androgen levels, challenging its categorization as idiopathic.
12 citations
,
January 2012 in “Dermatology” Finasteride helped treat a 28-year-old's facial skin condition.
67 citations
,
August 2004 in “Endocrinology” This study identified a novel I268T mutation in the vitamin D receptor that reduces its function, contributing to hereditary vitamin D-resistant rickets, and found that a potent vitamin D analog could improve receptor function.
3 citations
,
January 2019 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” This study found that idiopathic hirsutism was the most common cause of hirsutism among patients, and insulin resistance was significant in those with Hyperandrogenic Insulin Resistant Acanthosis Nigricans Syndrome.
10 citations
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May 2024 in “Lasers in Surgery and Medicine” This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.
March 2012 in “Hair transplant forum international” This abstract announces the third annual conference of the Association of Hair Restoration Surgeons in Mumbai in 2011 and reports no new clinical findings.
178 citations
,
October 2001 in “Genes & Development” This study found that the mammalian hairless gene encodes a corepressor protein that interacts with thyroid hormone receptors, providing insights into hair loss syndromes in humans and mice.
1 citations
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April 2008 in “Experimental Dermatology” This paper reviews hidradenitis suppurativa, comparing its clinical and histopathological characteristics to acne, questioning the proposed link to terminal hair follicles, and reports no new results.
12 citations
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February 2023 in “Stem Cell Research & Therapy” This study found that injecting hepatocyte growth factor-enhanced hair follicle stem cells into a rat model of ischemic stroke improved recovery by reducing inflammation, protecting the blood-brain barrier, and promoting angiogenesis.
66 citations
,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.
53 citations
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October 1984 in “Endocrine reviews” This review highlights that idiopathic hirsutism is characterized by local hyperandrogenization affecting hair growth, without other signs of hyperandrogenism, and shows no new results; racial differences in prevalence are noted but not in androgenic steroids.
1 citations
,
November 2025 in “Stem Cell Research & Therapy” This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.
April 2019 in “Journal of the Endocrine Society” This study found that androgen-regulated genes in hidradenitis suppurativa skin lesions are strongly linked to innate immunity pathways, indicating a potential connection between androgen signaling and inflammation in this condition.
2 citations
,
September 2021 in “Orphanet Journal of Rare Diseases” In this study, HED patients with COVID-19 showed a higher risk of postinfection fatigue and hair loss compared to controls, suggesting they are more susceptible to long-term consequences of SARS-CoV-2 infection.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper outlines the chronic inflammatory skin disorder hidradenitis suppurativa, emphasizing its symptomatology, associated systemic diseases, known risk factors, and treatment strategies, including medical and surgical interventions depending on disease severity, while highlighting its significant impact on patients' quality of life.
January 2024 in “Genetics in Medicine Open” This case study of a patient with a variant in the extracellular region of IL6ST suggests a potential expansion of the phenotypic spectrum for autosomal dominant hyper-IgE syndrome, warranting further investigation.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” This proof-of-concept study reported that a new, ultra-fast, one-step immunohistochemistry method improved the interpretation of Mohs surgery slides, particularly for poorly differentiated tumors.
This case report describes a novel mutation in the CDH3 gene in an 11-year-old Iranian boy with sparse scalp hair and macular dystrophy, leading to altered P-cadherin synthesis.
March 2005 in “International Journal of Cosmetic Science” This paper discusses the use of Digital Volumetric Imaging with fluorescent dyes to visualize and compare the interior structures of six different virgin hair types, reporting no new clinical results.
July 2026 in “Open Minds International Journal” This review suggests that multifunctional cosmetic systems, particularly HIVEN Curl Code ®, may help control frizz and maintain curl definition in highly curly hair by utilizing various conditioning and biofunctional ingredients.
4 citations
,
August 2006 in “The Journal of Dermatology” This case report describes the first known association of hypertrichosis lanuginosa acquisita with autoimmune hepatitis, expanding the list of conditions linked to this rare disorder.
1 citations
,
April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This article reviews the prevalence, causes, and associated conditions of hidradenitis suppurativa, a chronic inflammatory skin disease, but reports no new clinical findings.
April 2019 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.
1 citations
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April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical application of the HDAC1/3 inhibitor Vorinostat promoted hair regrowth in a mouse model of alopecia areata and influenced the hair cycle in normal mice.
1 citations
,
January 2016 in “Journal of Advanced Plastic Surgery Research” This study found that the LightSheer Diode EP Laser System significantly reduced hair growth among women with hirsutism, with side effects disappearing within three days and no long-term skin pigmentation issues observed.
December 2022 in “The Journal of Cosmetic Medicine” This study reports on a 46-year-old female with a high hairline who underwent hairline-lowering surgery using bone-tunneling suture fixation, achieving an average of 2 cm reduction, equivalent to transplanting up to 3,000 hair grafts, with satisfactory results for both patient and surgeons.
1 citations
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October 2025 in “Journal of Clinical Medicine” In this systematic review, researchers reported that various types of laser therapy effectively treat hidradenitis suppurativa at different severity stages, with each laser offering specific benefits such as lesion removal, inflammation reduction, and improved quality of life.