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Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Vitamin D is essential for bone health and may reduce risks of several diseases.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

NK cells play a role in skin diseases like eczema and psoriasis.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Uterine transplants for transgender women are feasible but need more research.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

The document concludes that Telogen Effluvium is a hair loss disorder that can be assessed with the modified wash test and may be treated with clobetasol foam, with patient management being important.

Epidermal nevi are skin cell clusters linked to various syndromes.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Cryotherapy helps reduce chemotherapy side effects but needs more research for best use.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

Edar signaling is crucial for controlling hair growth and regression.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Hidradenitis suppurativa might be a type of autoinflammatory skin disease.

JAK inhibitors show promise in effectively treating hair loss from alopecia areata.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.