3 citations
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August 2025 in “Cell” Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
1 citations
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December 2019 in “Clinical ophthalmology” This study found that bimatoprost eye drops increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits, without causing inflammation.
1 citations
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March 2018 in “Cureus” This review discusses scrotal rejuvenation procedures and treatments, highlighting a growing interest in this area due to increased awareness of potential scrotal conditions and available interventions.
June 2026 in “Journal of Comprehensive Dermatology” This study reviewed the evidence on minoxidil's effectiveness for androgenetic alopecia, finding that 5% topical minoxidil is the most effective monotherapy for men, while 2% is similarly effective for women. Genetic markers can predict response, and new formulations like foam and gel improve tolerability.
April 2026 in “microPublication” In this study, researchers explored whether minoxidil, a common treatment for androgenetic alopecia, may have estrogenic activity and found preliminary evidence suggesting it could act as a partial agonist of Estrogen Receptor α (ERα).
October 2025 in “American Journal of Clinical Dermatology” Low-dose oral minoxidil can effectively promote hair growth but requires careful monitoring for safety.
June 2025 in “Frontiers in Pharmacology” This systematic review and meta-analysis found that oral minoxidil improved hair loss symptoms in many patients, with significant improvement in 35%, but 27% experienced adverse events, highlighting the need for further research to confirm its safety and efficacy.
In this review, the authors highlight that drugs promoting androgenic activity or inhibiting estrogenic activity may unmask or worsen androgenetic alopecia in genetically predisposed individuals, indicating the need for careful management in clinical settings.
This review discusses anticoagulant and antihypertensive medications as potential contributors to medication-induced telogen effluvium and reports no new clinical results.
January 2023 in “Skin appendage disorders” This review discusses the potential of low-dose oral minoxidil as a safe and effective treatment for certain hair disorders, including alopecia, but reports no new clinical results.
January 2022 in “Function” This article analyzes the potential for insights from monogenic disorders to inform the understanding and treatment of common polygenic diseases, though complete predictability based on genotype remains unrealistic.
September 2024 in “Journal of Cosmetic Dermatology” This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.
148 citations
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May 2012 in “The American Journal of Human Genetics” This study identified heterozygous mutations in the ABCC9 gene as the genetic basis of Cantú syndrome, suggesting the syndrome as a new member of potassium channelopathies.
March 2025 in “Archives of Dermatological Research” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia, although more mild adverse events were reported compared to minoxidil alone.
January 2025 in “Dermatologic Therapy” This study found that adding low-dose oral minoxidil to standard treatment for lichen planopilaris was safe but did not significantly improve hair density or thickness, although minor hair regrowth was observed in some scarring areas.
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May 2024 in “Australasian Journal of Dermatology” This study assessed the psychosocial impact and disease burden of alopecia areata among adolescents and adults in Australia, finding substantial impacts on physical, emotional, and quality of life overall, with greater disease burden in patients experiencing more extensive hair loss.
131 citations
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March 2004 in “The American journal of pathology” This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
32 citations
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June 2013 in “Journal of Investigative Dermatology” This study found that reducing HDAC1 activity in the skin of mice led to defects in hair follicle structure and pigmentation, highlighting HDAC's role in skin and hair maintenance.
19 citations
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May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
January 2012 in “Postgraduate obstetrics & gynecology” This descriptive abstract provides information about a continuing medical education activity for physicians, designating 1.5 credits for participation, but reports no new research findings.
57 citations
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June 2003 in “American Journal of Physiology-cell Physiology” This study found that cyclosporin A treatment enhances hair growth in mice by inhibiting calcineurin-NFAT1 activity, which alters keratinocyte differentiation and apoptosis-related gene expression in hair follicles.
17 citations
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December 2015 in “BMC Complementary and Alternative Medicine” This study found that Avicennia marina extract significantly inhibited 5α-reductase type 1 activity in human hair dermal papilla cells, suggesting its potential use for treating androgenic alopecia.
12 citations
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February 2010 in “Tetrahedron Letters” This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.
11 citations
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March 2008 in “Experimental Dermatology” This study identified a thiazolidine dione derivative as a potential inhibitor of 15-PGDH that may enhance prostaglandin activity in hair follicles, suggesting its use to support hair regrowth treatments.
This article explores how natural and man-made factors shape architecture and environments for human activity in emergency situations, focusing on the unique conditions of the Republic of Kazakhstan. Results are not reported.
29 citations
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February 2003 in “Journal of Dermatology” This case report describes a woman with Becker's nevus and ipsilateral breast hypoplasia who showed breast enlargement after one month of spironolactone treatment, suggesting a link between hypoplasia and increased androgenic receptor activity.
21 citations
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April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
11 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study found that Blumea eriantha silver nanoparticles promoted hair growth in treated animals, with activity comparable to minoxidil in terms of anagen follicle transition.
25 citations
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January 2002 in “Folia Pharmacologica Japonica” This article reviews the proposed mechanism of minoxidil in treating androgenetic alopecia, suggesting it may prolong the anagen phase by modulating cell growth factors and vascular activity, but reports no new results.
34 citations
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May 2012 in “International Journal of Molecular Sciences” This study found that Ecklonia cava enzymatic extract, particularly its component dieckol, promoted hair growth by increasing dermal papilla cell proliferation and inhibiting 5α-reductase activity in cultured vibrissa follicles and C57BL/6 mice.