43 citations
,
November 2007 in “Dermatologic Clinics” This article discusses various hair and nail abnormalities linked to paraneoplastic conditions and cancer treatments, emphasizing their potential role in diagnosing and managing internal malignancies and reports no new clinical findings.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.
30 citations
,
November 2008 in “Facial Plastic Surgery” This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.
25 citations
,
July 2019 in “Experimental Dermatology” This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.
24 citations
,
July 2011 in “PubMed” This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.
March 2026 in “The Korean Society for Veterinary Nursing” In this study, Eremochloa ophiuroides-derived fractions were found to significantly promote hair regrowth in a mouse model, demonstrating effects comparable to minoxidil and suggesting potential as natural hair growth agents through modulation of follicular activation markers and growth-regulatory factors.
September 2025 in “Journal of King Saud University - Science” This study found that Lophocereus marginatus extracts significantly inhibited melanoma cell growth in vitro and stimulated hair growth in mice, with combined treatments of LM with minoxidil or bergamot showing notable effects by day 14 without altering body weight.
April 2024 in “Journal of cosmetic dermatology” This study found that SULT1A1 enzyme activity, crucial for activating minoxidil, is significantly lower in eyebrow and eyelash follicles compared to scalp follicles, suggesting that additional sulfotransferase supplementation might enhance minoxidil-based hair growth treatments for these areas.
May 2023 in “Scientific Reports” This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.
10 citations
,
August 1990 in “Journal of Steroid Biochemistry” High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
March 2022 in “Journal of The American Academy of Dermatology”
2 citations
,
January 2019 in “Annals of Dermatology” This preliminary study found that Melandrium firmum extract may promote hair growth and inhibit 5α-reductase, suggesting potential as a candidate for treating androgenetic alopecia.
8 citations
,
March 2005 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This case report describes a patient with glaucoma who developed reversible hyperpigmentation and hypertrichosis after using bimatoprost eye drops, aiming to explore prostaglandin analogues' potential roles in hair and depigmentation therapies.
March 2026 in “Materials Today Chemistry” Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.
April 2023 in “Journal of Investigative Dermatology” This study suggests that the CsA-induced inactivation of the CaN/NFAT pathway may suppress TGF-β2 expression in dermal papilla cells, potentially contributing to CsA-associated hypertrichosis.
16 citations
,
January 2018 in “International Journal of Trichology” In this study, minoxidil significantly downregulated interleukin-1 alpha expression in human keratinocyte cells, suggesting an anti-inflammatory effect that may be a mechanism of action in treating alopecia.
14 citations
,
December 2021 in “International journal of molecular sciences” This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.
In this study, incorporating cetirizine into transferosome formulations significantly enhanced hair growth in mice and boosted IGF-1 and VEGF levels, suggesting that this method could be a promising alternative to traditional hair growth treatments, though further studies are needed to confirm its safety and suitability.
August 2025 in “JAAD International” Bicalutamide may reduce hair shedding in women but needs longer trials to confirm its effectiveness.
April 2025 in “Materials Today Bio” In this study, researchers demonstrated that self-assembled gold nanoclusters with aptamers effectively deliver anti-NFκB aptamer drugs to inhibit hair follicle regeneration while being non-toxic to normal cells, offering a targeted treatment for hypertrichosis.
May 2023 in “International Journal of Trichology” This expert consensus discusses the potential use of oral minoxidil for treating alopecia and provides guidance to clinicians based on a comprehensive literature review and expert feedback; it reports no new clinical results.
December 2022 in “Cureus” This review discusses the hormonal impact on hair growth and the relationship between endocrine disorders and hair changes, reporting no new clinical results.
December 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This review of low-level laser therapy for patterned hair loss found that red-spectrum light may be effective for hair growth, but larger case-controlled studies are needed to further support this conclusion.
December 2025 in “Archives of Dermatological Research” This study reported safety concerns regarding minoxidil, noting risks of infantile hypertrichosis linked to maternal exposure and associations with eye disorders among users in the general population.
15 citations
,
September 2021 in “Journal of Clinical Medicine” This study observed that in children who unintentionally consumed high-dose oral minoxidil, 65% developed hypertrichosis, predominantly on the face, and 15% experienced mild systemic side effects.
June 2026 in “JAAD reviews.” This review suggests that low-dose oral minoxidil may enhance hair density in certain nonandrogenetic alopecias, but highlights the need for controlled trials due to mixed and limited evidence.
54 citations
,
July 1994 in “Journal of Dermatological Science” This study found that topical application of FK506 stimulated hair growth in animals, which may occur independently of its immunosuppressive effects, though its effect on human hair growth remains unclear.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” This article discusses the use of direct vasodilators and sympatholytic agents in hypertension management, highlighting their utility in specific cases like refractory hypertension and heart failure, but reports no new clinical results.
10 citations
,
January 2015 in “International Journal of Trichology” This study suggests that mechanical stress may influence androgenic alopecia patterning through a stretch-induced and androgen-mediated mechanotransduction mechanism in dermal papilla cells.