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    Glossary Hyperkeratotic Plaques

    thickened, rough skin patches due to excess keratin production

    Hyperkeratotic plaques are thickened, rough patches of skin that result from an overproduction of keratin, a protein that helps protect the skin. These plaques can appear scaly and are often associated with conditions like psoriasis or chronic eczema. For professionals, they indicate an underlying issue with skin cell turnover and may require treatments such as topical steroids or keratolytic agents to manage.

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    1. An Unusual Case of Tinea Capitis Presented as Erythematous, Hyperkeratotic, Scaly Plaque with Alopecia Indian Dermatology Online Journal · 2024
    2. 54269 Patchy hair loss, hyperpigmented plaques, and hyperkeratotic papules in a middle aged woman Journal of the American Academy of Dermatology · 2024
    3. Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma British Journal of Dermatology · 2013 · 2 citations
    4. Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3 Journal of Investigative Dermatology · 2014 · 56 citations
    5. Cutaneous Ultrastructural Features of the Flaky Skin (<i>fsn</i>) Mouse Mutation The Journal of Dermatology · 1995 · 28 citations
    6. Two familial cases of Olmsted-like syndrome with a G573V mutation of the<i>TRPV3</i>gene Clinical and experimental dermatology · 2016 · 12 citations
    7. Sebaceous carcinoma arising at a chronic candidiasis skin lesion of a patient with keratitis-ichthyosis-deafness (KID) syndrome British Journal of Dermatology · 2011 · 6 citations
    8. Scalp psoriasis associated with central centrifugal cicatricial alopecia Journal of Dermatology and Dermatologic Surgery · 2016
    9. Benign Mucous Membrane Pemphigoid Archives of Dermatology · 1979
    10. NEW ENGLAND DERMATOLOGICAL SOCIETY Archives of dermatology · 1974
    11. Characterizing Disease Features and Other Medical Diagnoses in Patients With Pityriasis Rubra Pilaris JAMA Dermatology · 2020 · 12 citations
    12. Olmsted syndrome Journal of Dermatological Case Reports · 2013 · 2 citations
    13. Cutaneous lupus erythematosus: clinico-pathologic correlation Italian Journal of Dermatology and Venereology · 2018 · 33 citations
    14. Disseminated Small Papules on the Face: A Quiz Acta dermato-venereologica · 2019 · 1 citations
    15. A new heterozygous frameshift variant in keratin 10 resulting in ichthyosis hystrix in a father and daughter JAAD case reports · 2023
    16. Frontal fibrosing alopecia: a case series of 65 patients seen in a single Italian centre Journal of the European Academy of Dermatology and Venereology · 2018 · 23 citations
    17. A combination of low-dose systemic etretinate and topical calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching in Olmsted syndrome associated with a TRPV3 mutation Journal of dermatological science · 2017 · 5 citations
    18. Zinc-responsive Acral Hyperkeratosis as a Sequele of Acrodermatitis Enteropathica Indian Journal of Paediatric Dermatology · 2025
    19. Proliferative, lymphocytic, infundibular mural folliculitis and dermatitis with prominent follicular apoptosis and parakeratotic casts in four Labrador retrievers: preliminary description and response to therapy Veterinary dermatology · 2013 · 10 citations
    20. Lupus cutáneo crónico Revista Dermatológica Centro Uraga · 2024
    21. Actinic Hyperkeratosis Treated with Retinol Combined with a Polylysine Biovector: A Case Report 2025
    22. Surgical Management of Severe Cicatricial Ectropion Secondary to Pityriasis Rubra Pilaris. Dermatologic Surgery · 2025
    23. Porokeratotic eccrine ostial and dermal duct nevus: A noteworthy presentation Indian Dermatology Online Journal · 2015 · 6 citations
    24. Gray Patch Tinea Capitis Caused by Microsporum canis Cermin Dunia Kedokteran · 2020 · 1 citations
    25. Ectopic acanthosis nigricans at a post-syndactyly surgical site: An unusual reactive epidermal phenomenon Journal of Cutaneous and Aesthetic Surgery · 2026
    26. Neonatal follicular mucinosis British Journal of Dermatology · 2007 · 10 citations
    27. Lichen planopilaris [cicatricial (scarring) alopecia] in a child International Journal of Dermatology · 2001 · 18 citations
    28. Case of follicular mucinosis: Nestin‐expression in mucin‐producing cells Journal of dermatology · 2009 · 1 citations
    29. Hypotrichosis and Hair Loss on the Occipital Scalp Cutis · 2023
    30. Porokeratotic adnexal ostial nevus: a paradigm of cutaneous mosaicism Authorea (Authorea) · 2022