Concurrence of Palmoplantar Psoriasiform Eruptions and Hair Loss During Carbamazepine Treatment
January 2008
in “
Acta dermato-venereologica
”
TLDR Carbamazepine caused hair loss and skin eruptions in a woman, which improved after stopping the medication.
The document reports a case of a 52-year-old woman who developed diffuse hair loss and palmoplantar psoriasiform eruptions after taking carbamazepine for facial pain due to an acoustic schwannoma. She had no history of psoriasis, alopecia, or other skin disorders. The symptoms began one month after starting carbamazepine and worsened over time. Upon reducing the dosage of carbamazepine, the psoriasiform eruptions improved within a week, and hair loss ceased four weeks later. Complete clearance of eruptions and spontaneous hair regrowth occurred after the drug was discontinued following surgery for the schwannoma. This case suggests that carbamazepine may be a causative agent for hair loss and psoriasiform eruptions, with the type of hair loss being telogen effluvium, which started two months after the initial administration of the medication. The document emphasizes the importance of recognizing potential adverse reactions to carbamazepine, including the possibility of inducing hair loss and psoriasiform eruptions concurrently.