TLDR Acitretin helped improve hand mobility and skin condition in a patient.
A patient with palmoplantar keratoderma and congenital alopecia experienced pseudoainhum, leading to restricted hand mobility. After several months of daily treatment with 25 mg of acitretin, the pseudoainhum resolved, and hyperkeratosis improved. This case suggested acitretin as a potential treatment for pseudoainhum, traditionally treated with reconstructive surgery.
14 citations
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June 1989 in “Journal of dermatology” Three siblings had both Vohwinkel's disease and congenital alopecia, with no effective treatment.
January 2018 in “Indian Dermatology Online Journal” A child with Olmsted syndrome showed mild improvement in hair and skin issues with treatment.
October 2024 in “Frontiers in Oncology” A new gene mutation linked to Olmsted syndrome may increase cancer risk, suggesting the need for ongoing patient monitoring.
25 citations
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March 2021 in “Australasian Journal of Dermatology” Ustekinumab successfully treated a man's resistant skin condition when other treatments failed.
66 citations
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June 2018 in “British Journal of Dermatology” European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
The document is a detailed guide on skin conditions and treatments for dermatologists.
