Resolution of Pseudoainhum with Acitretin Therapy in a Patient with Palmoplantar Keratoderma and Congenital Alopecia

    February 2019 in “ JAAD case reports ”
    Patricia M. Richey, Mary Seabury Stone
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    TLDR Acitretin helped improve hand mobility and skin condition in a patient.
    A patient with palmoplantar keratoderma and congenital alopecia experienced pseudoainhum, leading to restricted hand mobility. After several months of daily treatment with 25 mg of acitretin, the pseudoainhum resolved, and hyperkeratosis improved. This case suggested acitretin as a potential treatment for pseudoainhum, traditionally treated with reconstructive surgery.
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