December 2023 in “Journal of Asia Pacific Aesthetic Sciences” This study found that a novel method of isolating human follicle stem cells from hair follicles via mechanical centrifugation, without culture conditions, promises to improve hair density in patients with Androgenetic Alopecia and some cases of Alopecia Areata.
15 citations
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March 2021 in “Journal of Nanobiotechnology” This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.
June 2026 in “Virtual and Physical Prototyping” This study introduced a high-viscosity epoxy photoresist to enhance the fabrication of complex microstructures with monolithic integration and mechanical stability, enabling advancements in two-photon 3D printing for creating functional micro-mechanical devices.
This review investigates how the chirality of peptides affects their ability to form hydrogels, comparing the structural and mechanical properties of hydrogels made from homochiral and heterochiral peptides, and discussing their potential biological applications.
3 citations
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June 2017 in “Aesthetic plastic surgery” This study reported that novel adipose slurry injections improved rhytides and dermis density in patients receiving facial wrinkle treatments based on evaluations at multiple follow-up intervals.
84 citations
,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
20 citations
,
January 2006 in “Clinics in Plastic Surgery” This article discusses the benefits of tumescent surgery, such as reduced blood loss and pain control, but reports no new clinical findings.
January 2026 in “JPRAS Open” In this pilot study, PDLLA scalp microinjections showed improvement in physician-rated Global Aesthetic Improvement Scale scores over 12-24 weeks for 90% of patients with non-scarring alopecia, with no serious adverse events reported, although findings remain preliminary due to methodological limitations.
30 citations
,
November 2012 in “Proceedings of the Royal Society B Biological Sciences” This study found that the keratin matrix in mammalian hard α-keratins is crucial for maintaining stiffness in water by controlling intermediate filament hydration.
60 citations
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April 2003 in “Biomaterials” This study found that the controlled release of specific growth factors from biodegradable hydrogels significantly enhanced hair follicle growth and hair shaft length in mice compared to growth factors in solution.
June 2024 in “International journal of biological macromolecules” This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
March 2021 in “Indian Journal of Dermatology” A man unhappy with his old hair restoration got a new, natural-looking hairline using a combination of follicular unit extraction and punch graft reduction.
5 citations
,
January 2020 in “Skin Appendage Disorders” In this study, a water-soluble nail strengthener containing Pistacia lentiscus and hyaluronic acid significantly improved the appearance and firmness of brittle nails in both in vitro and clinical settings.
11 citations
,
July 2024 in “Biomimetics” This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.
December 2025 in “Cureus” This case report found that hyperbaric oxygen therapy significantly accelerated postoperative recovery in hair transplantation patients, improving healing, graft integration, and patient satisfaction without complications.
October 1997 in “Dermatologic Clinics” This study presents a proof-of-concept for a hybrid electric vehicle power system using a high temperature PEM fuel cell as a range extender, which may offer increased energy density with a methanol/water fuel mix.
87 citations
,
March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
January 1995 in “Surgical technology international” This review describes advances in alopecia-reducing procedures for cosmetic hair restoration, highlighting benefits and challenges, but reports no new clinical findings.
20 citations
,
October 2013 in “Dermatologic Surgery”
35 citations
,
October 2017 in “Trends in Molecular Medicine” This research suggests that targeting the HIF-1α pathway via PHD inhibitors may enable regeneration similar to amphibians in mammals, potentially fast-tracking regenerative therapies from mice to humans.
2 citations
,
April 2019 in “Experimental Dermatology” This study observed that applying a pulling force to hair follicles led to significant compression of nuclei in certain cell layers and distinct collagen changes at different follicle depths.
January 2000 in “Time to knit” This article reviews the advantages of emulgel as a topical drug delivery system for hydrophobic drugs but provides no new findings.
January 2020 in “한국공업화학회 연구논문 초록집” This study found that microencapsulated dermal papilla cells in hyaluronic acid/collagen hydrogel retained their ability to initiate hair follicle regeneration, suggesting potential for alopecia treatment.
11 citations
,
January 2024 in “Regenerative Biomaterials” This research reported that a newly developed dually crosslinked gelatin-alginate-based hydrogel scaffold enhances mechanical strength, promotes corneal tissue regeneration, and reduces scarring in rabbit models, suggesting potential applications in corneal tissue engineering.
34 citations
,
September 2020 in “Clinical, cosmetic and investigational dermatology” This research found that hyaluronic acid increased cell proliferation and type I collagen more effectively than poly-L-lactic acid in both human fibroblast cultures and rat dermis.
October 2025 in “Journal of Nanobiotechnology” This study reports that using a hydrogel-based therapy that dynamically regulates reactive oxygen species helps achieve skin regeneration in infected wounds, promoting organized dermal architecture with improved hair follicle and blood vessel formation, rather than scar formation.
80 citations
,
June 2008 in “Biomaterials” This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
January 2010 in “USFEU Scientific Library (Ural State Forest Engineering University)” This study developed a grooved microneedle platform enabling precise transdermal delivery of triamcinolone acetonide for alopecia areata, achieving accurate dosing by controlling groove position and drug concentration.
3 citations
,
January 2021 This chapter explains the mechanisms of facial aging and evaluates non-surgical treatments like thread lifts, platelet concentrates, high intensity focused ultrasound, and radio frequency for addressing aging signs, highlighting their potential for excellent patient outcomes.